<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Luc Verschaeve</style></author><author><style face="normal" font="default" size="100%">Birgit Mertens</style></author><author><style face="normal" font="default" size="100%">Ndhlala, A R</style></author><author><style face="normal" font="default" size="100%">Anthonissen, R</style></author><author><style face="normal" font="default" size="100%">Gorissen, B</style></author><author><style face="normal" font="default" size="100%">Van Staden, J</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Investigation into the genotoxicity of water extracts from Hypoxis species and a commercially available Hypoxis preparation.</style></title><secondary-title><style face="normal" font="default" size="100%">Phytother Res</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Phytother Res</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Comet Assay</style></keyword><keyword><style  face="normal" font="default" size="100%">DNA Damage</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Hypoxis</style></keyword><keyword><style  face="normal" font="default" size="100%">Mutagenicity Tests</style></keyword><keyword><style  face="normal" font="default" size="100%">Mutagens</style></keyword><keyword><style  face="normal" font="default" size="100%">Plant Extracts</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2013</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2013 Mar</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">27</style></volume><pages><style face="normal" font="default" size="100%">350-6</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;We performed an in vitro evaluation of the genotoxic potential of water extracts from four Hypoxis species (Hypoxis hemerocallidea, H. colchicifolia, H. rigidula, H. acuminata) and a commercial preparation thereof using the neutral red uptake (NRU) assay, the alkaline comet assay and the cytome assay in human hepatoma HepG2 cells. The relative cytotoxicity of these samples was established by determining their NI50 values (50% inhibition of NRU), and these results were used for dose-finding in genotoxicity tests. None of the tested extracts were identified as genotoxic in both the alkaline comet assay and cytome assay.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/22592975?dopt=Abstract</style></custom1></record></records></xml>