<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">De Smedt, T</style></author><author><style face="normal" font="default" size="100%">Koen De Cremer</style></author><author><style face="normal" font="default" size="100%">Christiane Vleminckx</style></author><author><style face="normal" font="default" size="100%">Sébastien Fierens</style></author><author><style face="normal" font="default" size="100%">Birgit Mertens</style></author><author><style face="normal" font="default" size="100%">Ilse Van Overmeire</style></author><author><style face="normal" font="default" size="100%">Bader, M</style></author><author><style face="normal" font="default" size="100%">De Paepe, P</style></author><author><style face="normal" font="default" size="100%">Göen, T</style></author><author><style face="normal" font="default" size="100%">Nemery, B</style></author><author><style face="normal" font="default" size="100%">Schettgen, T</style></author><author><style face="normal" font="default" size="100%">Stove, C</style></author><author><style face="normal" font="default" size="100%">Herman Van Oyen</style></author><author><style face="normal" font="default" size="100%">Joris Van Loco</style></author><author><style face="normal" font="default" size="100%">An Van Nieuwenhuyse</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Acrylonitrile exposure in the general population following a major train accident in Belgium: a human biomonitoring study.</style></title><secondary-title><style face="normal" font="default" size="100%">Toxicol Lett</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Toxicol. Lett.</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">acrylonitrile</style></keyword><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Belgium</style></keyword><keyword><style  face="normal" font="default" size="100%">Chemical Hazard Release</style></keyword><keyword><style  face="normal" font="default" size="100%">environmental exposure</style></keyword><keyword><style  face="normal" font="default" size="100%">Environmental Monitoring</style></keyword><keyword><style  face="normal" font="default" size="100%">Female</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">middle aged</style></keyword><keyword><style  face="normal" font="default" size="100%">Railroads</style></keyword><keyword><style  face="normal" font="default" size="100%">Sewage</style></keyword><keyword><style  face="normal" font="default" size="100%">Surveys and Questionnaires</style></keyword><keyword><style  face="normal" font="default" size="100%">Valine</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2014 Dec 15</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">231</style></volume><pages><style face="normal" font="default" size="100%">344-51</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;b&gt;BACKGROUND: &lt;/b&gt;On Saturday May 4, 2013, a train transporting chemicals derailed in the village of Wetteren (Belgium) and caused a leak of acrylonitrile (ACN).&lt;/p&gt;&lt;p&gt;&lt;b&gt;OBJECTIVES: &lt;/b&gt;To assess the human exposure to acrylonitrile in the local population with the highest suspected exposure.&lt;/p&gt;&lt;p&gt;&lt;b&gt;METHODS: &lt;/b&gt;Between May 18-25, 242 residents participated in the study. N-2-cyanoethylvaline (CEV), a biomarker that is highly specific for ACN exposure, was measured in the blood. To account for potential influence by smoking, cotinine was determined in the urine. Participants also filled in a short questionnaire.&lt;/p&gt;&lt;p&gt;&lt;b&gt;RESULTS: &lt;/b&gt;In the evacuated zone, 37.3% of the non-smokers and 40.0% of the smokers had CEV concentrations above the reference values of 10 and 200 pmol/g globin, respectively, at the time of the train accident. Spatial mapping of the CEV concentrations depending on the residential address showed a distribution pattern following the sewage system.&lt;/p&gt;&lt;p&gt;&lt;b&gt;DISCUSSION AND CONCLUSION: &lt;/b&gt;The train derailment resulted in a highly atypical sequence-of-events. In addition to exposure in the direct vicinity of the site of the train derailment, exposure also occurred via the sewage system, into which acrylonitrile had entered shortly after the accident.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/25223249?dopt=Abstract</style></custom1></record></records></xml>