<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Didier Breyer</style></author><author><style face="normal" font="default" size="100%">Philippe Herman</style></author><author><style face="normal" font="default" size="100%">Brandenburger, Annick</style></author><author><style face="normal" font="default" size="100%">Gheysen, Godelieve</style></author><author><style face="normal" font="default" size="100%">Remaut, Erik</style></author><author><style face="normal" font="default" size="100%">Soumillion, Patrice</style></author><author><style face="normal" font="default" size="100%">Van Doorsselaere, Jan</style></author><author><style face="normal" font="default" size="100%">Custers, René</style></author><author><style face="normal" font="default" size="100%">Katia Pauwels</style></author><author><style face="normal" font="default" size="100%">Myriam Sneyers</style></author><author><style face="normal" font="default" size="100%">Reheul, Dirk</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Genetic modification through oligonucleotide-mediated mutagenesis. A GMO regulatory challenge?</style></title><secondary-title><style face="normal" font="default" size="100%">Environ Biosafety Res</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Environ Biosafety Res</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Animals, Genetically Modified</style></keyword><keyword><style  face="normal" font="default" size="100%">European Union</style></keyword><keyword><style  face="normal" font="default" size="100%">genetic engineering</style></keyword><keyword><style  face="normal" font="default" size="100%">Government Regulation</style></keyword><keyword><style  face="normal" font="default" size="100%">International Cooperation</style></keyword><keyword><style  face="normal" font="default" size="100%">mutagenesis</style></keyword><keyword><style  face="normal" font="default" size="100%">Plants, Genetically Modified</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2009 Apr-Jun</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">57-64</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;In the European Union, the definition of a GMO is technology-based. This means that a novel organism will be regulated under the GMO regulatory framework only if it has been developed with the use of defined techniques. This approach is now challenged with the emergence of new techniques. In this paper, we describe regulatory and safety issues associated with the use of oligonucleotide-mediated mutagenesis to develop novel organisms. We present scientific arguments for not having organisms developed through this technique fall within the scope of the EU regulation on GMOs. We conclude that any political decision on this issue should be taken on the basis of a broad reflection at EU level, while avoiding discrepancies at international level.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">2</style></issue><custom1><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/19833073?dopt=Abstract</style></custom1></record></records></xml>