<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Svetlana V. Malysheva</style></author><author><style face="normal" font="default" size="100%">Séverine Goscinny</style></author><author><style face="normal" font="default" size="100%">Malarvannan, Govindan</style></author><author><style face="normal" font="default" size="100%">Poma, Giulia</style></author><author><style face="normal" font="default" size="100%">Mirjana Andjelkovic</style></author><author><style face="normal" font="default" size="100%">Voorspoels, Stefan</style></author><author><style face="normal" font="default" size="100%">Covaci, Adrian</style></author><author><style face="normal" font="default" size="100%">Joris Van Loco</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Development and validation of a quantitative UHPLC-MS/MS method for selected brominated flame retardants in food.</style></title><secondary-title><style face="normal" font="default" size="100%">Food Addit Contam Part A Chem Anal Control Expo Risk Assess</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">brominated flame retardants</style></keyword><keyword><style  face="normal" font="default" size="100%">bromophenols</style></keyword><keyword><style  face="normal" font="default" size="100%">Food Analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">HBCDsTBBPA</style></keyword><keyword><style  face="normal" font="default" size="100%">UHPLC-MS/MS</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2017 Oct 31</style></date></pub-dates></dates><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;An ultra-high performance liquid chromatography - tandem mass spectrometry (UHPLC-MS/MS) method was developed and validated (in-house) for the quantification of selected brominated flame retardants (BFRs), including tetrabromobisphenol A (TBBPA), hexabromocyclododecanes (HBCDs), tetrabromobisphenol S (TBBPS) and bromophenols (BPs), in various food matrices. The sample preparation consisted of extraction of TBBPS with acidified acetonitrile followed by a fast dispersive solid-phase extraction (dSPE) clean-up and extraction of the other BFRs with a mixture of hexane and dichloromethane (1:1, v/v) with subsequent clean-up using acidified silica (44%, w/w). The limits of quantification of the method varied widely for the types of food matrices and the different classes of BFRs from 4 pg g(-1) wet weight (ww) to 8 ng g(-1) ww. For most of the analytes the apparent recovery was in the range 70-120%, and the method precision (under repeatability conditions) was below 20%. The method was successfully applied in proficiency testing exercises as well as for analysis of various food items. Only 25% of the collected food samples contained BFRs, with 4-bromophenol and α-HBCD as the only detected compounds. The contaminated foodstuffs were fish and eggs with concentrations in the range from 48 to 305 pg g(-1) ww.&lt;/p&gt;
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