<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Raf Aerts</style></author><author><style face="normal" font="default" size="100%">Ilse Van Overmeire</style></author><author><style face="normal" font="default" size="100%">Ann Colles</style></author><author><style face="normal" font="default" size="100%">Mirjana Andjelkovic</style></author><author><style face="normal" font="default" size="100%">Govindan Malarvannan</style></author><author><style face="normal" font="default" size="100%">Giulia Poma</style></author><author><style face="normal" font="default" size="100%">Elly Den Hond</style></author><author><style face="normal" font="default" size="100%">Els Van de Mieroop</style></author><author><style face="normal" font="default" size="100%">Marie-Christine Dewolf</style></author><author><style face="normal" font="default" size="100%">François Charlet</style></author><author><style face="normal" font="default" size="100%">An Van Nieuwenhuyse</style></author><author><style face="normal" font="default" size="100%">Joris Van Loco</style></author><author><style face="normal" font="default" size="100%">Adrian Covaci</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Determinants of persistent organic pollutant (POP) concentrations in human breast milk of a cross-sectional sample of primiparous mothers in Belgium</style></title><secondary-title><style face="normal" font="default" size="100%">Environment International</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year></dates><volume><style face="normal" font="default" size="100%">131</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Background: Bio-accumulation of persistent organic pollutants (POPs) in the environment and in the food chain&lt;/p&gt;

&lt;p&gt;can lead to high pollutant concentrations in human fat-containing tissues and breast milk.&lt;/p&gt;

&lt;p&gt;Objectives: We aimed to identify the maternal characteristics that determined POP concentrations in breast milk&lt;/p&gt;

&lt;p&gt;of primiparous mothers in Belgium.&lt;/p&gt;

&lt;p&gt;Methods: Breast milk samples were obtained from a cross-sectional sample of 206 primiparous mothers in 2014.&lt;/p&gt;

&lt;p&gt;POP concentrations in breast milk samples were determined by GC-ECNI-MS and GC-EI-MS/MS depending on&lt;/p&gt;

&lt;p&gt;the analytes' sensitivity. Associations between POP concentrations in breast milk and potential determinants&lt;/p&gt;

&lt;p&gt;were investigated using two-way contingency tables and multivariable generalized linear models.&lt;/p&gt;

&lt;p&gt;Results: Fifteen of the 23 screened POPs were detected in the breast milk samples. Four organochlorine compounds&lt;/p&gt;

&lt;p&gt;(p,p′-DDT, p,p′-DDE, HCB and β-HCH) and two brominated flame retardant congeners (BDE-47, BDE-&lt;/p&gt;

&lt;p&gt;153) were detected at concentrations above the limit of quantification in&amp;gt;50% of the breast milk samples.&lt;/p&gt;

&lt;p&gt;Maternal age and BMI were usually associated with higher POP concentrations. Rural residency and consumption&lt;/p&gt;

&lt;p&gt;of home-produced eggs, fatty fish and fish oil supplements were associated with higher concentrations&lt;/p&gt;

&lt;p&gt;of DDT and DDE. Consumption of fatty fish and being breastfed during childhood were associated with higher&lt;/p&gt;

&lt;p&gt;concentrations of HCB and β-HCH. Fish oil supplements and home-produced eggs were associated with higher&lt;/p&gt;

&lt;p&gt;concentrations of BDEs, but for BDE congeners exposure routes other than diet require further investigation.&lt;/p&gt;

&lt;p&gt;Conclusions: Dietary and non-dietary determinants predict individual POP concentrations in breast milk.&lt;/p&gt;
</style></abstract><section><style face="normal" font="default" size="100%">104979</style></section></record></records></xml>