<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hantson, Philippe</style></author><author><style face="normal" font="default" size="100%">Arnaud Capron</style></author><author><style face="normal" font="default" size="100%">Wallemacq, Pierre</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Toxicokinetics of cocaine and metabolites in a body-packer becoming symptomatic.</style></title><secondary-title><style face="normal" font="default" size="100%">J Forensic Leg Med</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Adult</style></keyword><keyword><style  face="normal" font="default" size="100%">Cocaine</style></keyword><keyword><style  face="normal" font="default" size="100%">Crime</style></keyword><keyword><style  face="normal" font="default" size="100%">Electrocardiography</style></keyword><keyword><style  face="normal" font="default" size="100%">Forensic Toxicology</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Intestinal Obstruction</style></keyword><keyword><style  face="normal" font="default" size="100%">Male</style></keyword><keyword><style  face="normal" font="default" size="100%">Narcotics</style></keyword><keyword><style  face="normal" font="default" size="100%">Tachycardia, Sinus</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2011</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2011 Nov</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">18</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Life-threatening complications may occur in body-packers and the rupture of a single packet containing cocaine may lead to fatality. We report the case of a 35-year-old body-packer who developed at the airport clinical signs of cocaine toxicity. There was evidence of bowel obstruction. The plasma concentration of cocaine, benzoylecgonine (BZE) and ecgonine methyl ester (EME) was determined 1&amp;nbsp;h after symptoms onset, during surgery and postoperative period. The measured peak value at 1&amp;nbsp;h was 594&amp;nbsp;ng/ml for cocaine, 9423&amp;nbsp;ng/ml for BZE and 3261&amp;nbsp;ng/ml for EME. We confirm the following order BZE&amp;nbsp;&amp;gt;&amp;nbsp;EME&amp;nbsp;&amp;gt;&amp;nbsp;cocaine for peak plasma concentrations. A rebound in plasma levels was found during surgery, together with electrocardiographic changes. A total of 107 packets were eliminated, and the patient survived.&lt;/p&gt;
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