<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Thomas Mee</style></author><author><style face="normal" font="default" size="100%">Norman F Kirkby</style></author><author><style face="normal" font="default" size="100%">Noemie Dufourny</style></author><author><style face="normal" font="default" size="100%">Karen Joy Kirkby</style></author><author><style face="normal" font="default" size="100%">Neil G Burnet</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The use of radiotherapy, surgery and chemotherapy in the curative treatment of cancer: results from the FORTY (Favourable Outcomes from RadioTherapY) project</style></title><secondary-title><style face="normal" font="default" size="100%">The British Journal of Radiology</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Dec-10-2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">96</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong style=&quot;color:#69aa41;&quot;&gt;Objectives&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Radiotherapy, surgery and chemotherapy play key roles in the curative treatment of cancer, alone and in combination. Quantifying their roles is essential for equipment provision and workforce planning. The estimate that 40% of cancer patients are cured by RT has been used extensively to inform and influence policy but is relatively old and warrants review.&lt;/p&gt;

&lt;p&gt;&lt;strong style=&quot;color:#69aa41;&quot;&gt;Methods&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Patient, tumour and treatment event data was obtained for the 5 year period from 2009 to 2013, allowing a further 5 years for survival outcomes to be known. We analysed patient-level data on utilisation of surgery, radiotherapy, and chemotherapy in cancer patients in England. Data were sourced from Public Health England, using National Cancer Registrations, the National Radiotherapy Dataset (RTDS) and the Systemic Anti-Cancer Therapy Dataset (SACT). All tumour sites (excluding C44) and ages were included. We analysed three cohorts: all patients [n = 1,029,569], patients who survived 5 years or more [n = 537,970] and patients who survived &amp;lt;5 years [n = 491,599].&lt;/p&gt;

&lt;p&gt;&lt;strong style=&quot;color:#69aa41;&quot;&gt;Results&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;Overall cancer-specific 5-year survival was 52%, and in those patients, surgery was the most common curative treatment, with 80% receiving surgery, alone or in combination; radiotherapy was delivered to 39% and chemotherapy to 29%; 45% received two and 13% all three modalities.&lt;/p&gt;

&lt;p&gt;&lt;strong style=&quot;color:#69aa41;&quot;&gt;Conclusions&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;The high proportion receiving multimodality treatment emphasises the importance of integrated, resourced, multidisciplinary cancer care. Radiotherapy was delivered to almost 40% of patients who survived 5 years which underlines its importance in cancer management. Advances in knowledge The results are essential in planning cancer services. They also inform the public health narrative.&lt;/p&gt;
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