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Differential modulations of striatal tyrosine hydroxylase and dopamine metabolism by cannabinoid agonists as evidence for functional selectivity in vivo.

Public Access

Published

Peer reviewed scientific article

DOI : http://dx.doi.org/10.1016/j.neuropharm.2012.02.003 [1]

Authors

Bosier,B. [2]; Muccioli,G.G. [3]; Birgit Mertens [4]; Sarre,S. [5]; Michotte,Y. [6]; Didier M. Lambert [7]; Hermans,E. [8]

Keywords

  1. access [9]
  2. Activity [10]
  3. Adult [11]
  4. Agonist-selective coupling [12]
  5. an [13]
  6. analysi [14]
  7. analysis [15]
  8. AS [16]
  9. brain [17]
  10. cause [18]
  11. CB1 cannabinoid receptor [19]
  12. Control [20]
  13. data [21]
  14. Dopamine [22]
  15. DRUG [23]
  16. effect [24]
  17. effects [25]
  18. evidence [26]
  19. exposure [27]
  20. expression [28]
  21. Functional [29]
  22. G protein [30]
  23. GPCR [31]
  24. Increase [32]
  25. IS [33]
  26. metabolism [34]
  27. metabolites [35]
  28. ON [36]
  29. rats [37]
  30. Reduction [38]
  31. regulation [39]
  32. report [40]
  33. response [41]
  34. structure [42]
  35. System [43]
  36. Transmission [44]
  37. trend [45]
  38. Tyrosine hydroxylase [46]

Abstract:

It is generally assumed that cannabinoids induce transient modulations of dopamine transmission through indirect regulation of its release. However, we previously described a direct cannabinoid-mediated control of tyrosine hydroxylase (TH) expression,
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Source URL:https://sciensano.be/en/biblio/differential-modulations-striatal-tyrosine-hydroxylase-and-dopamine-metabolism-cannabinoid-agonists

Links
[1] http://dx.doi.org/10.1016/j.neuropharm.2012.02.003 [2] https://sciensano.be/en/biblio?f%5Bauthor%5D=2697&f%5Bsearch%5D=Bosier%2CB. [3] https://sciensano.be/en/biblio?f%5Bauthor%5D=2700&f%5Bsearch%5D=Muccioli%2CG.G. [4] https://sciensano.be/en/people/birgit-mertens/biblio [5] https://sciensano.be/en/biblio?f%5Bauthor%5D=2706&f%5Bsearch%5D=Sarre%2CS. [6] https://sciensano.be/en/biblio?f%5Bauthor%5D=2709&f%5Bsearch%5D=Michotte%2CY. [7] https://sciensano.be/en/biblio?f%5Bauthor%5D=2712&f%5Bsearch%5D=Didier%20M.%20Lambert [8] https://sciensano.be/en/biblio?f%5Bauthor%5D=2715&f%5Bsearch%5D=Hermans%2CE. [9] https://sciensano.be/en/biblio?f%5Bkeyword%5D=5394&f%5Bsearch%5D=access [10] https://sciensano.be/en/biblio?f%5Bkeyword%5D=945&f%5Bsearch%5D=Activity [11] https://sciensano.be/en/biblio?f%5Bkeyword%5D=2724&f%5Bsearch%5D=Adult [12] https://sciensano.be/en/biblio?f%5Bkeyword%5D=5397&f%5Bsearch%5D=Agonist-selective%20coupling [13] https://sciensano.be/en/biblio?f%5Bkeyword%5D=843&f%5Bsearch%5D=an [14] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1806&f%5Bsearch%5D=analysi [15] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1506&f%5Bsearch%5D=analysis [16] https://sciensano.be/en/biblio?f%5Bkeyword%5D=846&f%5Bsearch%5D=AS [17] https://sciensano.be/en/biblio?f%5Bkeyword%5D=5400&f%5Bsearch%5D=brain [18] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1323&f%5Bsearch%5D=cause [19] https://sciensano.be/en/biblio?f%5Bkeyword%5D=5403&f%5Bsearch%5D=CB1%20cannabinoid%20receptor [20] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1332&f%5Bsearch%5D=Control [21] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1335&f%5Bsearch%5D=data [22] https://sciensano.be/en/biblio?f%5Bkeyword%5D=5406&f%5Bsearch%5D=Dopamine [23] https://sciensano.be/en/biblio?f%5Bkeyword%5D=3015&f%5Bsearch%5D=DRUG [24] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1344&f%5Bsearch%5D=effect [25] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1347&f%5Bsearch%5D=effects [26] https://sciensano.be/en/biblio?f%5Bkeyword%5D=4107&f%5Bsearch%5D=evidence [27] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1350&f%5Bsearch%5D=exposure [28] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1689&f%5Bsearch%5D=expression [29] https://sciensano.be/en/biblio?f%5Bkeyword%5D=3963&f%5Bsearch%5D=Functional [30] https://sciensano.be/en/biblio?f%5Bkeyword%5D=5409&f%5Bsearch%5D=G%20protein [31] https://sciensano.be/en/biblio?f%5Bkeyword%5D=5412&f%5Bsearch%5D=GPCR [32] https://sciensano.be/en/biblio?f%5Bkeyword%5D=3591&f%5Bsearch%5D=Increase [33] https://sciensano.be/en/biblio?f%5Bkeyword%5D=525&f%5Bsearch%5D=IS [34] https://sciensano.be/en/biblio?f%5Bkeyword%5D=2301&f%5Bsearch%5D=metabolism [35] https://sciensano.be/en/biblio?f%5Bkeyword%5D=5415&f%5Bsearch%5D=metabolites [36] https://sciensano.be/en/biblio?f%5Bkeyword%5D=912&f%5Bsearch%5D=ON [37] https://sciensano.be/en/biblio?f%5Bkeyword%5D=5418&f%5Bsearch%5D=rats [38] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1785&f%5Bsearch%5D=Reduction [39] https://sciensano.be/en/biblio?f%5Bkeyword%5D=924&f%5Bsearch%5D=regulation [40] https://sciensano.be/en/biblio?f%5Bkeyword%5D=2388&f%5Bsearch%5D=report [41] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1584&f%5Bsearch%5D=response [42] https://sciensano.be/en/biblio?f%5Bkeyword%5D=2901&f%5Bsearch%5D=structure [43] https://sciensano.be/en/biblio?f%5Bkeyword%5D=933&f%5Bsearch%5D=System [44] https://sciensano.be/en/biblio?f%5Bkeyword%5D=681&f%5Bsearch%5D=Transmission [45] https://sciensano.be/en/biblio?f%5Bkeyword%5D=744&f%5Bsearch%5D=trend [46] https://sciensano.be/en/biblio?f%5Bkeyword%5D=5421&f%5Bsearch%5D=Tyrosine%20hydroxylase