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Evaluation of the residual solvent content of counterfeit tablets and capsules. [1]

Effectiveness and safety of vaccines, medicines and health products - Quality of medical laboratories   [2]

Peer reviewed scientific article

SCIENSANO

Authors

Eric Deconinck [3]; Michael Canfyn [4]; Sacré, P-Y [5]; Patricia Courselle [6]; De Beer, J O [7]

Keywords

  1. Capsules [8]
  2. Carbolines [9]
  3. Counterfeit Drugs [10]
  4. Gas Chromatography-Mass Spectrometry [11]
  5. Guidelines as Topic [12]
  6. Phosphodiesterase 5 Inhibitors [13]
  7. Piperazines [14]
  8. Purines [15]
  9. Sildenafil Citrate [16]
  10. Solvents [17]
  11. Sulfones [18]
  12. Tablets [19]
  13. Tadalafil [20]

Abstract:

A group of counterfeit samples of Viagra and Cialis were screened for their residual solvent content and compared to the content of the genuine products. It was observed that all counterfeit samples had higher residual solvent contents compared to the genuine products. A more diverse range of residual solvents was found as well as higher concentrations. In general these concentrations did not exceed the international imposed maximum limits. Only in a few samples the limits were exceeded. A Projection Pursuit analysis revealed clusters of samples with similar residual solvent content, possib…
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Associated health topics:

Effectiveness and safety of vaccines, medicines and health products - Quality of medical laboratories [2]
Source URL:https://sciensano.be/en/biblio/evaluation-residual-solvent-content-counterfeit-tablets-and-capsules

Links
[1] https://sciensano.be/en/biblio/evaluation-residual-solvent-content-counterfeit-tablets-and-capsules [2] https://sciensano.be/en/health-topics/effectiveness-and-safety-vaccines-medicines-and-health-products-quality-medical-laboratories [3] https://sciensano.be/en/people/eric-deconinck/biblio [4] https://sciensano.be/en/people/michael-canfyn/biblio [5] https://sciensano.be/en/biblio?f%5Bauthor%5D=48501&f%5Bsearch%5D=Sacr%C3%A9%2C%20P-Y [6] https://sciensano.be/en/people/patricia-courselle/biblio [7] https://sciensano.be/en/biblio?f%5Bauthor%5D=46698&f%5Bsearch%5D=De%20Beer%2C%20J%20O [8] https://sciensano.be/en/biblio?f%5Bkeyword%5D=18957&f%5Bsearch%5D=Capsules [9] https://sciensano.be/en/biblio?f%5Bkeyword%5D=23553&f%5Bsearch%5D=Carbolines [10] https://sciensano.be/en/biblio?f%5Bkeyword%5D=18798&f%5Bsearch%5D=Counterfeit%20Drugs [11] https://sciensano.be/en/biblio?f%5Bkeyword%5D=18723&f%5Bsearch%5D=Gas%20Chromatography-Mass%20Spectrometry [12] https://sciensano.be/en/biblio?f%5Bkeyword%5D=21030&f%5Bsearch%5D=Guidelines%20as%20Topic [13] https://sciensano.be/en/biblio?f%5Bkeyword%5D=23580&f%5Bsearch%5D=Phosphodiesterase%205%20Inhibitors [14] https://sciensano.be/en/biblio?f%5Bkeyword%5D=23562&f%5Bsearch%5D=Piperazines [15] https://sciensano.be/en/biblio?f%5Bkeyword%5D=23565&f%5Bsearch%5D=Purines [16] https://sciensano.be/en/biblio?f%5Bkeyword%5D=32598&f%5Bsearch%5D=Sildenafil%20Citrate [17] https://sciensano.be/en/biblio?f%5Bkeyword%5D=3363&f%5Bsearch%5D=Solvents [18] https://sciensano.be/en/biblio?f%5Bkeyword%5D=23571&f%5Bsearch%5D=Sulfones [19] https://sciensano.be/en/biblio?f%5Bkeyword%5D=18966&f%5Bsearch%5D=Tablets [20] https://sciensano.be/en/biblio?f%5Bkeyword%5D=32610&f%5Bsearch%5D=Tadalafil