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Mycobacterium tuberculosis with disruption in genes encoding the phosphate binding proteins PstS1 and PstS2 is deficient in phosphate uptake and demonstrates reduced in vivo virulence., Peirs, Priska, Lef\'e8vre Philippe, Boarbi Samira, Wang Xiao-Ming, Denis Olivier J., Braibant Martine, Pethe Kevin, Locht Camille, Huygen Kris, and Content Jean , Infect Immun, 2005 Mar, Volume 73, Issue 3, p.1898-902, (2005)\par \par }