<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>6</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">H.J. de Haard</style></author><author><style face="normal" font="default" size="100%">A. Hultberg</style></author><author><style face="normal" font="default" size="100%">Verrips,T.</style></author><author><style face="normal" font="default" size="100%">Vanlandschoot,P.</style></author><author><style face="normal" font="default" size="100%">Saunders,M.</style></author><author><style face="normal" font="default" size="100%">Stortelers,C.</style></author><author><style face="normal" font="default" size="100%">Steven Van Gucht</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Rupprecht,C.</style></author><author><style face="normal" font="default" size="100%">Nagarajan,T.</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Chapter Twenty Seven - Generation of immune globulin single variable domains by display technologies</style></title><secondary-title><style face="normal" font="default" size="100%">Current Laboratory Techniques in Rabies Diagnosis, Research and Prevention</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">antibodies</style></keyword><keyword><style  face="normal" font="default" size="100%">Antibody</style></keyword><keyword><style  face="normal" font="default" size="100%">Diagnosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Epitopes</style></keyword><keyword><style  face="normal" font="default" size="100%">Genetic</style></keyword><keyword><style  face="normal" font="default" size="100%">Glycoprotein</style></keyword><keyword><style  face="normal" font="default" size="100%">Heavy-Chain Antibody Fragments</style></keyword><keyword><style  face="normal" font="default" size="100%">Immune Globulin Single Variable Domains</style></keyword><keyword><style  face="normal" font="default" size="100%">Laboratories</style></keyword><keyword><style  face="normal" font="default" size="100%">llama</style></keyword><keyword><style  face="normal" font="default" size="100%">nanobody</style></keyword><keyword><style  face="normal" font="default" size="100%">ON</style></keyword><keyword><style  face="normal" font="default" size="100%">Phage Display</style></keyword><keyword><style  face="normal" font="default" size="100%">prevention</style></keyword><keyword><style  face="normal" font="default" size="100%">Rabies</style></keyword><keyword><style  face="normal" font="default" size="100%">Rabies virus</style></keyword><keyword><style  face="normal" font="default" size="100%">Research</style></keyword><keyword><style  face="normal" font="default" size="100%">Selection</style></keyword><keyword><style  face="normal" font="default" size="100%">strain</style></keyword><keyword><style  face="normal" font="default" size="100%">Target</style></keyword><keyword><style  face="normal" font="default" size="100%">Technique</style></keyword><keyword><style  face="normal" font="default" size="100%">technology</style></keyword><keyword><style  face="normal" font="default" size="100%">Variable domain on Heavy-Chain (VHH)</style></keyword><keyword><style  face="normal" font="default" size="100%">VHH</style></keyword><keyword><style  face="normal" font="default" size="100%">VIRUS</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2015</style></year><pub-dates><date><style  face="normal" font="default" size="100%">0/0/2015</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">302</style></number><edition><style face="normal" font="default" size="100%">332</style></edition><publisher><style face="normal" font="default" size="100%">Academic Press</style></publisher><pub-location><style face="normal" font="default" size="100%">Amsterdam</style></pub-location><volume><style face="normal" font="default" size="100%">1</style></volume><pages><style face="normal" font="default" size="100%">332</style></pages><isbn><style face="normal" font="default" size="100%">978-0-12-800014-4</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Rabies virus-specific, cross-neutralizing, llama-derived heavy-chain antibody fragments (VHH) can be generated rapidly from immune llamas using phage display technology. The selection procedure can be tailor-made depending on the epitope to be targeted, whereas the single-chain nature of the VHH allows for facile genetic fusion of different VHH to create multivalent VHH. These VHH can target one or several different epitopes, thereby increasing the chance of neutralization of different strains of virus</style></abstract><custom1><style face="normal" font="default" size="100%">37450</style></custom1><section><style face="normal" font="default" size="100%">291</style></section></record></records></xml>