Résultats de la recherche - 53 results
Phage-Mediated Digestive Decolonization in a Gut-On-A-Chip Model: A Tale of Gut-Specific Bacterial Prosperity.
a worthy alternative in this context. Taking inspiration from this clinical challenge, we built Gut-On-A-Chip (GOAC) models, which are tridimensional cell culture models mimicking a simplified gut section. ...
Regulatory workshop on challenge strain development and GMP manufacture- A stakeholder meeting report.
Klaas Smits, Wiep; Stoughton, Daniel; Talaat, Kawsar; Vehreschild, Maria J G T; Wildfire, Adrian; Meln, Irina; Olesen, Ole F Source: Biologicals, Volume 85 (2024) Keywords: Clostridioides difficile Humans ...
VERMEER FCM: A tool integrating exposure and hazard modelling for chemicals migrating from food contact materials
Hoeck; Birgit Mertens Source: Food and Chemical Toxicology, Volume 193 (2024) Keywords: food contact materials Hazard prediction In silico Migration Modelling VEGA Abstract: A new tool, VERMEER FCM, was ...
A roadmap for regulatory implementation of in vitro models for evaluation of vaccine efficacy
Publication Type: Scientific poster, presentation or proceeding Authors: R. J. Vandebriel; L. Tesolin; K. Veenstra; K. Huber Source: EVI, Niagara falls, Canada (2023) Keywords: in vitro model ...
WP20 Regulatory. Workshop outcome, dissemination, gaps, and next steps: from models to showcases
Scientific posters, presentations and proceedings FOS Classification: 1.6 Biological sciences ...
A healthy lifestyle is positively associated with mental health and well-being and core markers in ageing
using qPCR. Generalised linear mixed models were used while adjusting for a priori chosen covariates. RESULTS: The average age (SD) of the study population was 49.9 (17.5) years, and 48.8% were men. ...
Residential green space in association with the methylation status in a CpG site within the promoter region of the placental serotonin receptor HTR2A
these associations are already evident during foetal development. Similar biological signals shape the developmental processes in the foetal brain and placenta.Therefore, we hypothesize that green space ...
Considerations on the principles of development and manufacturing qualities of challenge agents for use in human infection models
Classification: 1.6 Biological sciences ...
Identifying nanodescriptors to predict the toxicity of nanomaterials: a case study on titanium dioxide
outcome of computational modelling. In this study, we aim to identify nanodescriptor(s) and biological endpoint(s) capable of predicting the toxicity of titanium-di-oxide (TiO2) NM s, and demonstrate how ...
Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.
Keywords: Biological Products Drug Development Human Experimentation Humans vaccines whole genome sequencing Abstract: Controlled human infection models can be helpful to study pathogenesis and immune ...