Résultats de la recherche - 34 results
Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.
no indication of genotoxicity and a low ecotoxicological footprint. Mode-of-action studies revealed that P1-type nucleoside transporters and adenosine kinase are involved in the uptake and activation, ...
Herpes zoster in Belgium: a new solution to an old problem
immunocompromised patients aged ≥ 16 years, including those receiving immunosuppressive therapy, in particular Janus kinase inhibitors. RZV showed high age-independent efficacy in preventing HZ infection and in ...
The phage-encoded PIT4 protein affects multiple two-component systems of Pseudomonas aeruginosa
studied that impacts key virulence factors of the pathogen via interaction with multiple histidine kinases of TCS s. The fundamental insights gained for this protein can therefore serve as inspiration for ...
Insights From Early Clinical Trials Assessing Response to mRNA SARS-CoV-2 Vaccination in Immunocompromised Patients.
lower response to the vaccine such as anti- CD19, anti- CD20 or anti- CD38 therapies, low (naive) CD4 T-cell counts, genetic or therapeutic Bruton tyrosine kinase deficiency, treatment with ...
HPV DNA genotyping, HPV E6*I mRNA detection, and p16INK4a/Ki-67 staining in Belgian head and neck cancer patient specimens, collected within the HPV-AHEAD study
80 and over Alphapapillomavirus Belgium Cyclin-Dependent Kinase Inhibitor p16 DNA, Viral Female Genotype Head and Neck Neoplasms Head and neck neoplasms; Human papillomavirus; Human papillomavirus DNA ...
Meta-analysis of the accuracy of p16 or p16/Ki-67 immunocytochemistry versus HPV testing for the detection of CIN2+/CIN3+ in triage of women with minor abnormal cytology.
Atypical Squamous Cells of the Cervix Cyclin-Dependent Kinase Inhibitor p16 Cytodiagnosis Early Detection of Cancer Female Humans immunohistochemistry Ki-67 Antigen Papillomaviridae Papillomavirus Infections ...
Role of mucosal high-risk human papillomavirus types in head and neck cancers in central India.
Aged Cyclin-Dependent Kinase Inhibitor p16 Female Head and Neck Neoplasms Humans India Male middle aged Papillomaviridae Papillomavirus Infections Abstract: Mucosal high-risk (HR) human papillomaviruses ...
Us3 and Us9 proteins contribute to the stromal invasion of bovine herpesvirus 1 in the respiratory mucosa.
kinase, induces a dramatic cytoskeletal reorganization and BHV-1 Us9, a tail-anchored membrane protein, is required for axonal transport of viruses in neurons. In this study, we investigated the role of Us3 ...
PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes.
3 (2017) Keywords: Alkanes Animals astrocytes Calcium Signaling Cyclopropanes Glial Fibrillary Acidic Protein immunohistochemistry Lentivirus Methoxyhydroxyphenylglycol Primary Cell Culture Protein Kinase ...
Diagnostic accuracy of p16(INK4a) immunohistochemistry in oropharyngeal squamous cell carcinomas: A systematic review and meta-analysis.
(2017) Keywords: Biomarkers, Tumor Carcinoma, Squamous Cell Cell Transformation, Viral Cyclin-Dependent Kinase Inhibitor p16 DNA, Viral Humans In Situ Hybridization Neoplasm Proteins Oncogene Proteins, ...