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cytotoxicity

Résultats de la recherche - 10 results

A systematic review and meta-analysis of human population studies on the association between exposure to toxic environmental chemicals and left ventricular dysfunction (LVD).

longitudinal and case-control studies to confirm further risk associations. These studies should consider co-exposures, account for vulnerable groups, and identify cardiotoxic compounds that may require ...

Pollutant exposure and myocardial injury: Protocol and progress report for a toxicological systematic mapping review.

result in CVD are not fully understood. To comprehensively describe and understand the pathways through which pollutant exposure leads to cardiotoxicity, a systematic mapping review of the available ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Birgit Mertens Source: 57th Congress of the European Societies of Toxicology, Ljubljana, Slovenia (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment ...

Innovative non-animal based testing platform to detect chemical-induced cardiotoxicity- A roadmap for regulatory uptake

Birgit Mertens Source: Joint 3R Symposium, Brussels, Belgium (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to testing and assessment (IATA) pollutants Health Topics:  ...

Reducing the Burden on Animals and the Heart: An Evidence-Based Approach to Cardiotoxicity Assessment

Martin Paparella Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: adverse outcome pathways Cardiotoxicity Integrated approaches to ...

A Systematic Review on Pollutant Induced Cardiotoxicity: Providing a Toxicological Foundation for NAM Development and Regulatory Acceptance

Ritskes-Hoitinga; R. Gehring Source: 12th World Congress on Alternatives and Animal Use in the Life Sciences, Nigara falls, Canada (2023) Keywords: Cardiotoxicity pollutants systematic review toxicological evidence ...

Cardiotoxicity of chemicals: Current regulatory guidelines, knowledge gaps, and needs.

Publication Type: Peer reviewed scientific article Authors: Alexandra Schaffert; Sivakumar Murugadoss *; Birgit Mertens *; Martin Paparella Source: Volume 40, Issue 2 (2023) Keywords: Cardiotoxicity ...

Cardiotoxicity of chemicals: Current regulatory guidelines, knowledge gaps, and needs.

Cardiotoxicity environmental exposure Hazardous Substances Humans Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Manuscript versions:  DOI:  ...

Pesticide regulations and cardiotoxicity

Publication Type: Scientific poster, presentation or proceeding Authors: Philippe Castelain Source: (2021) Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Efficacité et sécurité des vaccins, médicaments et produits de sa ...

Severe acute cardiomyopathy associated with venlafaxine overdose and possible role of CYP2D6 and CYP2C19 polymorphisms.

a serotonin-norepinephrine-dopamine reuptake inhibitor that causes usually a mild cardiotoxicity when ingested in overdose. We report a patient who developed acute heart failure following overdose. As the toxicokinetic data suggested ...

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