Determination of vaccine bacterial endotoxins content by the rFC method

Determination of vaccine bacterial endotoxins content by the rFC method [1]

Efficacité et sécurité des vaccins, médicaments et produits de santé - Qualité des laboratoires médicaux [2]

Scientific poster, presentation or proceeding

Anglais

SCIENSANO

Auteurs

Flore Laurent [3]

Mots-clés

Résumé:

Sciensano, as official medicines control laboratory (OMCL) following “Official Control Authority Batch Release” (OCABR) guidelines, is entitled to check the concentration of endotoxin in bacterial vaccines. The limulus amebocyte lysate (LAL) and the recombinant factor C (rFC) assays are suitable for all vaccines tested. The rFC method has been implemented at Sciensano for batch release of vaccines since March 2023.

Associated health topics:

Efficacité et sécurité des vaccins, médicaments et produits de santé - Qualité des laboratoires médicaux [2]