<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Aline Baldo</style></author><author><style face="normal" font="default" size="100%">Galanis, Evanthia</style></author><author><style face="normal" font="default" size="100%">Tangy, Frédéric</style></author><author><style face="normal" font="default" size="100%">Philippe Herman</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Biosafety considerations for attenuated measles virus vectors used in virotherapy and vaccination.</style></title><secondary-title><style face="normal" font="default" size="100%">Hum Vaccin Immunother</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Hum Vaccin Immunother</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Animals</style></keyword><keyword><style  face="normal" font="default" size="100%">Containment of Biohazards</style></keyword><keyword><style  face="normal" font="default" size="100%">Genetic Vectors</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Measles</style></keyword><keyword><style  face="normal" font="default" size="100%">Measles Vaccine</style></keyword><keyword><style  face="normal" font="default" size="100%">Measles virus</style></keyword><keyword><style  face="normal" font="default" size="100%">Membrane Cofactor Protein</style></keyword><keyword><style  face="normal" font="default" size="100%">mice</style></keyword><keyword><style  face="normal" font="default" size="100%">Oncolytic Virotherapy</style></keyword><keyword><style  face="normal" font="default" size="100%">Vaccination</style></keyword><keyword><style  face="normal" font="default" size="100%">Vaccines, Attenuated</style></keyword><keyword><style  face="normal" font="default" size="100%">Virus Internalization</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2016 May 03</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">1116</style></number><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1102-16</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Attenuated measles virus (MV) is one of the most effective and safe vaccines available, making it attractive candidate vector to prevent infectious diseases. Attenuated MV have acquired the ability to use the complement regulator CD46 as a major receptor to mediate virus entry and intercellular fusion. Therefore, attenuated MV strains preferentially infect and destroy a wide variety of cancer cells making them also attractive oncolytic vectors. The use of recombinant MV vector has to comply with various regulatory requirements, particularly relating to the assessment of potential risks for human health and the environment. The present article highlights the main characteristics of MV and recombinant MV vectors used for vaccination and virotherapy and discusses these features from a biosafety point of view.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><custom1><style face="normal" font="default" size="100%">https://www.ncbi.nlm.nih.gov/pubmed/26631840?dopt=Abstract</style></custom1><section><style face="normal" font="default" size="100%">1102</style></section></record></records></xml>