Genesis and Spread of Novel Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Genotype EA-2023-DG Reassortant, Western Europe.
Diergezondheid
Peer reviewed scientific article
Engels
SCIENSANO
Auteurs
Steven Van Borm [1]; Ahrens, Ann Kathrin [2]; Bachofen, Claudia [3]; Banyard, Ashley C [4]; Bøe, Cathrine Arnason [5]; Briand, François-Xavier [6]; Dirbakova, Zuzana [7]; Engelsma, Marc [8]; Fusaro, Alice [9]; Germeraad, Evelien [10]; Gjerset, Britt [11]; Grasland, Béatrice [12]; Harders, Frank [13]; Hostyn, Pierre [14]; Kauppinen, Ari [15]; Bénédicte Lambrecht [16]; Mollett, Benjamin C [17]; Monne, Isabella [18]; Nagy, Alexander [19]; Pohlmann, Anne [20]; Polzer, Daniel [21]; Reid, Scott M [22]; Revilla-Fernandez, Sandra [23]; Mieke Steensels * [24]; Stätter, Michaela [25]; Swieton, Edyta [26]; Tammiranta, Niina [27]; Wyler, Michele [28]; Zecchin, Bianca [29]; Zohari, Siamak [30]; Dellicour, Simon [31]Trefwoorden
Samenvatting:
In Europe, highly pathogenic avian influenza (HPAI) virus circulates in avian wildlife, undergoing frequent reassortment, sporadic introductions in domestic birds, and spillover to mammals. An H5N1 clade 2.3.4.4b reassortant, EA-2023-DG, affecting wild and domestic birds was detected in western Europe in November 2023. Six of its RNA segments came from the EA-2021-AB genotype, but the polymerase basic 2 and polymerase acidic segments originated from low pathogenicity avian influenza viruses. Discrete phylogeographic analyses of concatenated genomes and single polymerase basic 2 and polymera…