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Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Publication Type: Peer reviewed scientific article Authors: Musiu, Simone; Pürstinger, Gerhard; Stallinger, Sylvia; Vrancken, Robert; Andy Haegeman; F. Koenen; Leyssen, Pieter; Froeyen, Mathy; ...
Intra-host variation structure of classical swine fever virus NS5B in relation to antiviral therapy.
Publication Type: Peer reviewed scientific article Authors: Andy Haegeman; Vrancken, Robert; Neyts, Johan; F. Koenen Source: Antiviral Res, Volume 98, Issue 2, p.266-72 (2013) Keywords: Amino Acid ...
Classical swine fever: comparison of oronasal immunisation with CP7E2alf marker and C-strain vaccines in domestic pigs.
Publication Type: Peer reviewed scientific article Authors: Marylène Tignon; Kulcsár, Gábor; Andy Haegeman; Barna, Timea; Fábián, Katalin; Lévai, Réka; Yves Van der Stede; Farsang, Attila; Vrancken ...
Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor.
Publication Type: Peer reviewed scientific article Authors: Vrancken, Robert; Andy Haegeman; Paeshuyse, Jan; Puerstinger, Gerhard; Rozenski, Jef; Wright, Matthew; Marylène Tignon; Le Potier, ...
A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.
Publication Type: Peer reviewed scientific article Authors: Paeshuyse, Jan; Letellier, Carine; Froeyen, Matheus; Dutartre, Hélène; Vrancken, Robert; Canard, Bruno; De Clercq, Erik; Gueiffier, Alain; ...
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication.
Publication Type: Peer reviewed scientific article Authors: Paeshuyse, Jan; Chezal, Jean-Michel; Froeyen, Matheus; Leyssen, Pieter; Dutartre, Hélène; Vrancken, Robert; Canard, Bruno; Letellier, ...
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase.
Publication Type: Peer reviewed scientific article Authors: Paeshuyse, Jan; Leyssen, Pieter; Mabery, Eric; Boddeker, Nina; Vrancken, Robert; Froeyen, Matheus; Ansari, Israrul H; Dutartre, Hélène; ...