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In vitro and in vivo local tolerability of a synergistic anti-tuberculosis drug combination intended for pulmonary delivery.
and monocytes were exposed to concentrations around and above their minimal inhibitory concentration (MIC). The VAN had no inhibitory activity on the tested human cell lines, even at a concentration 125 ...
Anti-mycobacterial activity of 1,3-diaryltriazenes.
its potential as anti-tubercular agent. Several compounds were identified with sub-micro molar inhibitory concentrations against M. tuberculosis and other clinically relevant mycobacterial species such ...
Biological evaluation of diazene derivatives as anti-tubercular compounds.
observed minimal inhibitory concentrations below 10 μg/mL against the H37R v lab strain of M.tb. Three compounds that showed a potency of 90% growth inhibition of M.tb at a concentration lower than 10 μg/mL ...
Factors Influencing Benzene Formation from the Decarboxylation of Benzoate in Liquid Model Systems
concentrations, and the inhibitory effect of antioxidants were tested in benzoate containing model systems. Regarding the hydroxyl radical sources tested, the highest benzene formation was observed in light exposed ...
Mutagenicity, antimutagenicity and cytotoxicity evaluation of South African Podocarpus species
inhibitory and antioxidant activities. AIM OF THE STUDY: To investigate the mutagenicity, antimutagenicity and cytotoxicity effects of leaf and stem extract of South African Podocarpus species. MATERIAL AND ...
Pharmacokinetics of a loading dose of amikacin in septic patients undergoing continuous renal replacement therapy87
using a validated fluorescence polarisation immunoassay method. In 9 patients (69%) the peak concentration was >64 mg/L, which corresponds to eight times the minimal inhibitory concentration ...
A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.
Substitution Animals Antiviral Agents Benzodioxoles Cattle Cell Line Diarrhea Virus 1, Bovine Viral Diarrhea Virus 2, Bovine Viral Drug Resistance, Viral Hepacivirus Inhibitory Concentration 50 Models, Molecular ...
Synthesis and biological activity of endomorphin-2 analogs incorporating piperidine-2-, 3- or 4-carboxylic acids instead of proline in position 24391
chemistry Comparison electronic Functional im Inhibitory Concentration 50 Institute IS journal Laboratories medical Oligopeptides Piperidines Proline rats Receptor receptors Receptors,Opioid,mu Research ...
Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase.
Three-Dimensional Imidazoles Inhibitory Concentration 50 Models, Molecular Molecular Structure polymerase chain reaction Pyridines RNA Replicase RNA, Viral Sequence Analysis, DNA Structure-Activity Relationship Virus ...
Detection of tetracycline-resistant and susceptible pasteurellaceae in the nasopharynx of loose group-housed calves.
farm this proved to be an OTC-resistant subpopulation. Minimum inhibitory concentration (MIC) determinations by means of agar dilution confirmed a low prevalence of OTC-resistant Pasteurellaceae, with ...