Search results - 618 results

Targeted Whole Genome Sequencing of the Capripoxvirus Genome from Clinical Tissue Samples and Lyophilized Vaccine Batches.

are of great economic importance in sheep, goats, and cattle. Since CaPV strains are serologically indistinguishable and genetically highly homologous, typing of closely related strains can only be ...

Regulatory workshop on challenge strain development and GMP manufacture- A stakeholder meeting report.

a significant challenge for developers. Still, it is preferred over reverse genetics challenge strains for several reasons, including implications and regulations around genetically modified organisms (GMO s). ...

Unlocking the genomic landscape: Results of the Beyond 1 Million Genomes (B1MG) pilot in Belgium towards Genomic Data Infrastructure (GDI)

Belgium Beyond 1 Million Genomes Genomic Data Infrastructure implementation Abstract: Abstract Genomic medicine has great potential to offer insights into how humans’ genetic variation can affect their ...

Complete genome reconstruction of the global and European regional dispersal history of the lumpy skin disease virus.

circulation of vaccine-like recombinants, and the use of vaccines. The slow molecular evolution of its DNA genome limits the utility of genetic variation for accurate tracing based on evolutionary analyses, but ...

Complete genome reconstruction of the global and European regional dispersal history of the lumpy skin disease virus.

circulation of vaccine-like recombinants, and the use of vaccines. The slow molecular evolution of its DNA genome limits the utility of genetic variation for accurate tracing based on evolutionary analyses, but ...

Strain-level characterization without culture enrichment? Easing and accelerating outbreak investigation using shotgun metagenomics facilitated with nanopore adaptive sampling

resolved. Shotgun metagenomics is a sequencing method involving the analysis of the genetic material directly extracted from a sample, without the need for an isolation of the bacteria. By sequencing and ...

Genomic monitoring of SARS-CoV-2 variants using sentinel SARI hospital surveillance.

monitor general trends and early signals of viral genetic evolution of SARS-CoV-2 and compare it with the BGS as a reference model. METHODS: Nine-hundred twenty-five SARS-CoV-2 positive samples from ...

Oncolytic Viruses: An Inventory of Shedding Data from Clinical Trials and Elements for the Environmental Risk Assessment.

environmental risk assessment oncolytic virus shedding Abstract: Attenuated and/or genetically modified oncolytic viruses (OV) gain increasing interest as a promising approach for cancer therapy. Beside the ...

Genomic strategies to track unauthorized genetically modified microorganisms in fermentation products used in the food chain

Publication Type: Scientific poster, presentation or proceeding Authors: Marie-Alice Fraiture; Jolien D'aes Source: BRIAS, ULB-VUB, Online & Brussels, Belgium (2023) Service:  Activités transversales en génomique appliquée Transversale activiteit ...

Application of the Nagoya Protocol to veterinary pathogens: concerns for the control of foot-and-mouth disease.

Sci, Volume 10 (2023) Abstract: The Nagoya Protocol is an international agreement adopted in 2010 (and entered into force in 2014) which governs access to genetic resources and the fair and equitable ...

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