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Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.
Caljon, Guy Source: ACS Infect Dis, Volume 11, Issue 1 (2025) Keywords: Animals Disease Models, Animal Drug Discovery Drug Evaluation, Preclinical Humans mice Nucleosides Trypanocidal Agents Trypanosoma ...
Assessment of receptor-mediated activity (AhR and ERα), mutagenicity, and teratogenicity of metal shredder wastes in Wallonia, Belgium.
GTP-Binding Proteins Hazardous Waste Industrial Waste Metals mice mutagenesis Receptors, Aryl Hydrocarbon RNA-Binding Proteins Salmonella typhimurium Zebrafish Abstract: In this study, hazardous wastes ...
The future burden of type 2 diabetes in Belgium: a microsimulation model.
Chained Equations (MICE) as inputs to the Simulation of Synthetic Complex Data (simPop) model. Mortality information was obtained from the Belgian vital statistics and used to calculate annual death ...
Replacement of Diphtheria and Tetanus potency challenge method by serology in mice
Publication Type: Scientific poster, presentation or proceeding Authors: J. Auquier Source: Annual OMCL Meeting 2023, EDQM, Madrid (2023) Keywords: 3R Diphtheria serology Tetanus vaccine Health Topics: Vaccin Vaccin Vaccin Service: Qualité des vaccins e ...
Sex difference in innate inflammatory response and macrophage polarization in Streptococcus agalactiae-induced pneumonia and potential role of microRNA-223-3p.
1 (2022) Keywords: Animals Antagomirs Cytokines Female Inflammation Macrophages Male mice MicroRNAs Pneumonia Sex Characteristics Streptococcus agalactiae Abstract: While number of studies have shown that ...
Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial
observed for rebaudioside A in mice, they have been attributed to the metabolites steviol and steviol glucuronide. We aimed to characterize the pharmacokinetic and pharmacodynamic properties of rebaudioside ...
A Role for B Cells to Transmit Hepatitis C Virus Infection.
B-Lymphocytes Broadly Neutralizing Antibodies Disease Models, Animal Female Hepacivirus Hepatitis C Humans Liver Liver Transplantation Male mice middle aged serum Transplantation Chimera Vaccine Development Viral ...
Lentiviral vector induces high-quality memory T cells via dendritic cells transduction.
Lentivirus mice Mice, Inbred C57BL Promoter Regions, Genetic Transduction, Genetic Transgenes Abstract: We report a lentiviral vector harboring the human β2-microglobulin promoter, with predominant expression ...
In-vivo expressed Mycobacterium tuberculosis antigens recognised in three mouse strains after infection and BCG vaccination.
in three different mouse strains. Eleven Mtb-antigens were recognised across TB-resistant and susceptible mice. Confirming previous human data, several Mtb-antigens induced cytokines other than IFN-γ. ...
Update of the risk assessment of hexabromocyclododecanes (HBCDDs) in food
in mice can be considered the critical effects. Based on effects on spontaneous behaviour in mice, the Panel identified a lowest observed adverse effect level (LOAEL) of 0.9 mg/kg body weight (bw) as ...