Search results - 59 results
Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.
Caljon, Guy Source: ACS Infect Dis, Volume 11, Issue 1 (2025) Keywords: Animals Disease Models, Animal Drug Discovery Drug Evaluation, Preclinical Humans mice Nucleosides Trypanocidal Agents Trypanosoma ...
Advancing the Replacement of animal testing in Toxicology via the RE-Place platform
https://www.sciensano.be/en/biblio/advancing-replacement-animal-testing-toxicology-re-place-platform
non-clinical safety testing strategies for the development of human medicinal products’, Issue BelTox & BEMS, Ghent, Belgium (2024) Keywords: 3Rs Database Knowledge sharing NAMs new approach methodologies ...
Physicochemical characterization and genotoxicity assessment of nanomaterials using new approach methodologies
Committee et al., Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health, EFS2 19, (2021). [3] REGULATION (EU) 2015/ 2283 OF THE ...
Assessment of receptor-mediated activity (AhR and ERα), mutagenicity, and teratogenicity of metal shredder wastes in Wallonia, Belgium.
contamination, the mutagenicity, and the teratogenicity of these shredder wastes raise significant concerns about their potential negative impacts on both human health and environment. Health Topics: Health and ...
Antimicrobial resistance in ESBL and indicator E. coli, Campylobacter spp.,Salmonella spp., methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus faecalis and faecium isolated from food and food-producing animals (primary production) in 2023
antibiotic resistance genes, present in both humans and animals. In 2023, the prevalences of enterococci species by animal category were similar to those observed in previous years. Indeed, Enterococcus ...
Towards a more effective REACH legislation in protecting human health.
Belleghem, Frank; Vanoirbeek, Jeroen; Van Larebeke, Nicolas Source: Toxicol Sci, Volume 199, Issue 2 (2024) Keywords: Animals Belgium environmental exposure Hazardous Substances Humans Risk Assessment Toxicity ...
Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals.
* Source: Chem Res Toxicol, Volume 37, Issue 3 (2024) Keywords: Animals Biomarkers Cell Line DNA Damage Gene Expression Profiling Humans Transcriptome Abstract: To modernize genotoxicity assessment and reduce ...
Animal sources of antimicrobial-resistant bacterial infections in humans: a systematic review
defined as livestock, aquaculture, pets, and animal-based food, on human AMR. We searched four scientific databases and identified 31 relevant publications, including 12 risk assessments, 16 source ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells
genetic toxicology GENOMARK biomarker predictive toxicology human health risk assessment new approach methodologies (NAMs) Abstract: Transcriptomics-based biomarkers are promising new approach methodologies ...