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Establishing disease models for the Belgian national burden of disease study: challenges and perspectives
contains all cases. This parent node then gives rise to multiple “child nodes”, with the terminal child nodes representing the individual health states. In BeBOD, disease models and severity distributions ...
The increasing significance of disease severity in a burden of disease framework
burden of disease severity distribution Years lived with disability YLD Abstract: Recent estimates have reiterated that non-fatal causes of disease, such as low back pain, headaches and depressive ...
Sex difference in innate inflammatory response and macrophage polarization in Streptococcus agalactiae-induced pneumonia and potential role of microRNA-223-3p.
biological sex is a risk factor in the incidence and severity of infection-induced inflammatory diseases, the underlying mechanisms are still poorly understood. In this study, we compared the innate ...
Mapping EQ-5D utilities to GBD 2010 and GBD 2013 disability weights: results of two pilot studies in Belgium.
attributed a relatively higher severity level to musculoskeletal disorders such as ‘Amputation of both legs’ and a relatively lower severity level to non-functional disorders such as ‘Headache migraine’ ...
Revisiting the loading dose of amikacin for patients with severe sepsis and septic shock90
in conditions associated with an increased volume of distribution (Vd), such as severe sepsis and septic shock. The primary aim of this study was to determine whether 25 mg/kg (total body weight) of ...
Validation of a liquid chromatography-mass spectrometric assay for tacrolimus in liver biopsies after hepatic transplantation: correlation with histopathologic staging of rejection.
rejection episodes (BANFF < 6). In this study, hepatic tissue TAC concentrations were distributed in a wider range and displayed a significantly better correlation with the severity of the organ rejection ...