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Home > Biblio > Has Epizootic Become Enzootic? Evidence for a Fundamental Change in the Infection Dynamics of Highly Pathogenic Avian Influenza in Europe, 2021.

Has Epizootic Become Enzootic? Evidence for a Fundamental Change in the Infection Dynamics of Highly Pathogenic Avian Influenza in Europe, 2021.

Animal health  
[1]
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Public Access

Published

Peer reviewed scientific article

English

DOI : https://doi.org/10.1128/mbio.00609-22 [2]

Authors

Anne Pohlmann [3]; Jacqueline King [4]; Fusaro, Alice [5]; Bianca Zecchin [6]; Ashley C Banyard [7]; Brown, Ian H [8]; Alexander M P Byrne [9]; Nancy Beerens [10]; Liang, Yuan [11]; Rene Heutink [12]; Frank Harders [13]; Joe James [14]; Scott M Reid [15]; Rowena D E Hansen [16]; Nicola S Lewis [17]; Charlotte Hjulsager [18]; Lars E Larsen [19]; Siamak Zohari [20]; Kristofer Anderson [21]; Caroline Bröjer [22]; Alexander Nagy [23]; Vladimir Savič [24]; Steven Van Borm [25]; Mieke Steensels [26]; Briand, François-Xavier [27]; Edyta Swieton [28]; Smietanka, Krzysztof [29]; Christian Grund [30]; Beer, Martin [31]; Timm Harder [32]

Keywords

  1. Animals [33]
  2. Animals, Wild [34]
  3. Birds [35]
  4. Europe [36]
  5. Influenza A virus [37]
  6. Influenza A Virus, H5N1 Subtype [38]
  7. Influenza in Birds [39]
  8. Phylogeny [40]
  9. Poultry [41]

Abstract:

Phylogenetic evidence from the recent resurgence of high-pathogenicity avian influenza (HPAI) virus subtype H5N1, clade 2.3.4.4b, observed in European wild birds and poultry since October 2021, suggests at least two different and distinct reservoirs. We propose contrasting hypotheses for this emergence: (i) resident viruses have been maintained, presumably in wild birds, in northern Europe throughout the summer of 2021 to cause some of the outbreaks that are part of the most recent autumn/winter 2021 epizootic, or (ii) further virus variants were reintroduced by migratory birds, and these t…
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Abstract

Phylogenetic evidence from the recent resurgence of high-pathogenicity avian influenza (HPAI) virus subtype H5N1, clade 2.3.4.4b, observed in European wild birds and poultry since October 2021, suggests at least two different and distinct reservoirs. We propose contrasting hypotheses for this emergence: (i) resident viruses have been maintained, presumably in wild birds, in northern Europe throughout the summer of 2021 to cause some of the outbreaks that are part of the most recent autumn/winter 2021 epizootic, or (ii) further virus variants were reintroduced by migratory birds, and these two sources of reintroduction have driven the HPAI resurgence. Viruses from these two principal sources can be distinguished by their hemagglutinin genes, which segregate into two distinct sublineages (termed B1 and B2) within clade 2.3.4.4b, as well as their different internal gene compositions. The evidence of enzootic HPAI virus circulation during the summer of 2021 indicates a possible paradigm shift in the epidemiology of HPAI in Europe.

Associated health topics:

Avian influenza [42]

Source URL:https://sciensano.be/en/biblio/has-epizootic-become-enzootic-evidence-a-fundamental-change-infection-dynamics-highly-pathogenic

Links
[1] https://sciensano.be/sites/default/files/mbio.00609-22.pdf [2] https://doi.org/10.1128/mbio.00609-22 [3] https://sciensano.be/en/biblio?f%5Bauthor%5D=185586&f%5Bsearch%5D=Anne%20Pohlmann [4] https://sciensano.be/en/biblio?f%5Bauthor%5D=185587&f%5Bsearch%5D=Jacqueline%20King [5] https://sciensano.be/en/biblio?f%5Bauthor%5D=37629&f%5Bsearch%5D=Fusaro%2C%20Alice [6] https://sciensano.be/en/biblio?f%5Bauthor%5D=185588&f%5Bsearch%5D=Bianca%20Zecchin [7] https://sciensano.be/en/biblio?f%5Bauthor%5D=185589&f%5Bsearch%5D=Ashley%20C%20Banyard [8] https://sciensano.be/en/biblio?f%5Bauthor%5D=37647&f%5Bsearch%5D=Brown%2C%20Ian%20H [9] https://sciensano.be/en/biblio?f%5Bauthor%5D=185590&f%5Bsearch%5D=Alexander%20M%20P%20Byrne [10] https://sciensano.be/en/biblio?f%5Bauthor%5D=185591&f%5Bsearch%5D=Nancy%20Beerens [11] https://sciensano.be/en/biblio?f%5Bauthor%5D=185592&f%5Bsearch%5D=Liang%2C%20Yuan [12] https://sciensano.be/en/biblio?f%5Bauthor%5D=185593&f%5Bsearch%5D=Rene%20Heutink [13] https://sciensano.be/en/biblio?f%5Bauthor%5D=185594&f%5Bsearch%5D=Frank%20Harders [14] https://sciensano.be/en/biblio?f%5Bauthor%5D=185595&f%5Bsearch%5D=Joe%20James [15] https://sciensano.be/en/biblio?f%5Bauthor%5D=185596&f%5Bsearch%5D=Scott%20M%20Reid [16] https://sciensano.be/en/biblio?f%5Bauthor%5D=185597&f%5Bsearch%5D=Rowena%20D%20E%20Hansen [17] https://sciensano.be/en/biblio?f%5Bauthor%5D=185598&f%5Bsearch%5D=Nicola%20S%20Lewis [18] https://sciensano.be/en/biblio?f%5Bauthor%5D=185599&f%5Bsearch%5D=Charlotte%20Hjulsager [19] https://sciensano.be/en/biblio?f%5Bauthor%5D=185600&f%5Bsearch%5D=Lars%20E%20Larsen [20] https://sciensano.be/en/biblio?f%5Bauthor%5D=184626&f%5Bsearch%5D=Siamak%20Zohari [21] https://sciensano.be/en/biblio?f%5Bauthor%5D=185601&f%5Bsearch%5D=Kristofer%20Anderson [22] https://sciensano.be/en/biblio?f%5Bauthor%5D=185602&f%5Bsearch%5D=Caroline%20Br%C3%B6jer [23] https://sciensano.be/en/biblio?f%5Bauthor%5D=185603&f%5Bsearch%5D=Alexander%20Nagy [24] https://sciensano.be/en/biblio?f%5Bauthor%5D=185604&f%5Bsearch%5D=Vladimir%20Savi%C4%8D [25] https://sciensano.be/en/people/steven-van-borm/biblio [26] https://sciensano.be/en/people/mieke-steensels/biblio [27] https://sciensano.be/en/biblio?f%5Bauthor%5D=37653&f%5Bsearch%5D=Briand%2C%20Fran%C3%A7ois-Xavier [28] https://sciensano.be/en/biblio?f%5Bauthor%5D=185605&f%5Bsearch%5D=Edyta%20Swieton [29] https://sciensano.be/en/biblio?f%5Bauthor%5D=37692&f%5Bsearch%5D=Smietanka%2C%20Krzysztof [30] https://sciensano.be/en/biblio?f%5Bauthor%5D=185606&f%5Bsearch%5D=Christian%20Grund [31] https://sciensano.be/en/biblio?f%5Bauthor%5D=37755&f%5Bsearch%5D=Beer%2C%20Martin [32] https://sciensano.be/en/biblio?f%5Bauthor%5D=185607&f%5Bsearch%5D=Timm%20Harder [33] https://sciensano.be/en/biblio?f%5Bkeyword%5D=423&f%5Bsearch%5D=Animals [34] https://sciensano.be/en/biblio?f%5Bkeyword%5D=28539&f%5Bsearch%5D=Animals%2C%20Wild [35] https://sciensano.be/en/biblio?f%5Bkeyword%5D=2415&f%5Bsearch%5D=Birds [36] https://sciensano.be/en/biblio?f%5Bkeyword%5D=42&f%5Bsearch%5D=Europe [37] https://sciensano.be/en/biblio?f%5Bkeyword%5D=27801&f%5Bsearch%5D=Influenza%20A%20virus [38] https://sciensano.be/en/biblio?f%5Bkeyword%5D=27831&f%5Bsearch%5D=Influenza%20A%20Virus%2C%20H5N1%20Subtype [39] https://sciensano.be/en/biblio?f%5Bkeyword%5D=27804&f%5Bsearch%5D=Influenza%20in%20Birds [40] https://sciensano.be/en/biblio?f%5Bkeyword%5D=4914&f%5Bsearch%5D=Phylogeny [41] https://sciensano.be/en/biblio?f%5Bkeyword%5D=1293&f%5Bsearch%5D=Poultry [42] https://sciensano.be/en/health-topics/avian-influenza