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Batch release of vaccines in Europe: from method transfer to first commercial batch available on the market. Straightforward approach that requires a proactive mindset of the manufacturer.
sometimes a lengthy process. Sometimes more than one year should be taken into account between the intention of putting a vaccine on the market and the first available commercial batch. Since OCABR in EU is ...
Impact of DNA extraction on whole genome sequencing analysis for characterization and relatedness of Shiga toxin-producing Escherichia coli isolates.
laboratories is essential to support foodborne pathogen control, including outbreak investigation. This study evaluated eight commercial DNA preparation kits for their potential influence on: (i) DNA quality for ...
Evaluation of seven commercial African swine fever virus detection kits and three Taq polymerases on 300 well-characterized field samples.
sensitivity and specificity of seven commercially available ASFV real-time PCR detection kits and three Taq polymerases on 300 well-characterized wild boar samples collected in Belgium during the 2018-2019 ...
Changes in retail food environments around schools over 12 years and associations with overweight and obesity among children and adolescents in Flanders, Belgium.
primary and secondary schools was mapped using spatial indicators. The commercial Locatus database, including addresses of all food retailers in Flanders, was used to calculate the density of different ...
A new open strategy for impurity surveillance of commercial microbial fermentation food products
Publication Type: Scientific poster, presentation or proceeding Authors: Marie-Alice Fraiture; Nancy Roosens; N. Papazova; Sigrid C.J. De Keersmaecker; Kevin Vanneste; Rik Orval; Yari Van Laere; Frédéric Debode; Marc De Loose; Christof Van Poucke; Nathali ...
Occurrence of Perillaldehyde and Other (Suspected) Genotoxic Flavoring Substances in Water-Based Beverages Consumed by Belgian Children
Perillaldehyde and furan-2(5H)-one, two genotoxic flavoring substances, were found at concentrations up to 153 and 143 μg·kg –1, respectively. Perillaldehyde levels were significantly higher in commercial citrus ...
Identification of an unauthorized genetically modified bacteria in food enzyme through whole-genome sequencing.
Recently, the unexpected presence of a viable unauthorized genetically modified bacterium in a commercialized food enzyme (protease) product originating from a microbial fermentation process has been notified ...
Combined untargeted screenings of substances migrating from emerging food contact materials
followed by spectral matching with commercial mass spectral libraries. A data reduction strategy based on procedural blank subtraction was also applied to improve further data analysis. Finally, the ...
Accelerating vaccine manufacturing development through model-based approaches: current advances and future opportunities
Abstract: This review highlights the importance of model-based approaches in accelerating vaccine manufacturing process development. The challenges of scaling up from laboratory to commercial processes are ...
Comparative Analysis of Different Serological and Molecular Tests for the Detection of Small Ruminant Lentiviruses (SRLVs) in Belgian Sheep and Goats.
extensive comparative analysis of seven commercially available serological tests and one in-house real-time PCR (qPCR) detecting genotype A and B strains using a large panel of representative Belgian field ...