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Use of Strep-tag II for rapid detection and purification of Mycobacterium tuberculosis recombinant antigens secreted by Streptomyces lividans
Publication Type: Peer reviewed scientific article Authors: Ayala,J.C.; Pimienta,E.; Rodriguez,C.; J. Anné; Vallin,C.; Milanes,M.T.; King-Batsios,E.; K Huygen; Van Mellaert,L. Source: ...
Synthesis and antimycobacterial activity of analogues of the bioactive natural products sampangine and cleistopholine36497
Publication Type: Peer reviewed scientific article Authors: Claes,P.; D. Cappoen; Mbala,B.M.; J. Jacobs; Birgit Mertens; Vanessa Mathys; Luc Verschaeve; K Huygen; N. De Kimpe Source: ...
Mucosal and systemic immune responses to Mycobacterium tuberculosis antigen 85A following its co-delivery with CpG, MPLA or LTB to the lungs in mice1377
Publication Type: Peer reviewed scientific article Authors: Todoroff,J.; Lemaire,MM.; Fillee,C.; Fabienne Jurion; J.C. Renauld; K Huygen; R. Vanbever Source: PLoS ONE, Volume 8, Issue 5, p.e63344 ...
M.tuberculosis mutants lacking oxygenated mycolates show increased immunogenicity and protective efficacy as compared to M. bovis BCG vaccine in an experimental mouse model.
Publication Type: Peer reviewed scientific article Authors: Hedhli, Dorsaf; Olivier J Denis; Barkan, Daniel; Daffé, Mamadou; Glickman, Michael S; Huygen, Kris Source: PLoS One, Volume 8, Issue 10, ...
Clinical value of IS6110-based loop-mediated isothermal amplification for detection of Mycobacterium tuberculosis complex in respiratory specimens
Publication Type: Peer reviewed scientific article Authors: Aryan,E.; Makvandi,M.; Farajzadeh,A.; K Huygen; Alvandi,A.H.; Gouya,M.M.; Sadrizadeh,A.; Marta Romano Source: J.Infect., Volume 66, Issue ...
Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery34028
Publication Type: Peer reviewed scientific article Authors: Todoroff,J.; Ucakar,B.; Inglese,M.; Vandermarliere,S.; Fillee,C.; J.C. Renauld; K Huygen; R. Vanbever Source: Eur.J.Pharm.Biopharm., ...
Biological evaluation of bisbenzaldehydes against four Mycobacterium species.
Vanden Eynde, Jean Jacques; Huygen, Kris Source: Eur J Med Chem, Volume 63, p.731-8 (2013) Keywords: Animals Anti-Bacterial Agents Antitubercular Agents Benzaldehydes Cell Line Cell Survival Cells, ...
Hooping cough in adults, think about it!
Publication Type: Peer reviewed scientific article Authors: Toukouki,A.; Frippiat,F.; Frusch,N.; Caprasse,P.; Meuris,C.; C Rodeghiero; R. Vanhoof; Denis Piérard; Moutschen,M.; K Huygen; Giot,J.B. ...
Induction of the specific allergic immune response is independent of proteases from the fungus Alternaria alternata.
Publication Type: Peer reviewed scientific article Authors: Denis, Olivier; Vincent, Muriel; Havaux, Xavier; De Prins, Sofie; Treutens, Greta; Huygen, Kris Source: Eur J Immunol, Volume 43, Issue 4, ...
Lymph node targeting of BCG vaccines amplifies CD4 and CD8 T-cell responses and protection against Mycobacterium tuberculosis34032
Publication Type: Peer reviewed scientific article Authors: Waeckerle-Men,Y.; Nicolas Bruffaerts; Liang,Y.; Fabienne Jurion; Sander,P.; Kundig,T.M.; K Huygen; Johansen,P. Source: Vaccine, Volume 31, ...