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European Antimicrobial Resistance Surveillance Network (EARS-Net Belgium)- Report 2017 (Data up to and including 2016)
them. Resistance arises in three ways: natural (intrinsic) resistance in certain types of bacteria, or acquired via either genetic mutation, or by horizontal gene transfer. The European Antimicrobial ...
A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.
profiles; phenotypic resistance to isoniazid, rifampicin, ethambutol, pyrazinamide, and capreomycin; and corresponding drug resistance mutations. We whole-genome sequenced all Mycobacterium tuberculosis ...
What can the CF registry tell us about rare CFTR-mutations? A Belgian study.
Abstract: BACKGROUND: CFTR2 provides clinical and functional information of the most common CFTR-mutations. Rare mutations (RM s) occur in only a few patients with limited reported clinical data. Their role ...
Effect of allergic bronchopulmonary aspergillosis on FEV1 in children and adolescents with cystic fibrosis: a European Cystic Fibrosis Society Patient Registry analysis.
significant (p>0.05). For patients aged 11.82 years (population mean age), poor body mass index had the greatest impact on FEV1 in 2008, followed by high-risk genotype (two severe mutations), female gender, ...
Antimutagenicity, antioxidant activity and cytotoxicity of n-tetracosanol, eiocosanoic acid and arjunolic acid isolated from Combretum microphyllum (Combretaceae)
acid exposure Follow Hepatocytes Human investigation LED medicinal plant methanol extract method methods Mutagens Mutation n-Tetracosanol ON plant Plant Extracts Plants PROCESSES result results ...
Ethnicity impacts the cystic fibrosis diagnosis: A note of caution.
analysis of the CFTR2 and UK CF databases for clinical phenotype, sweat chloride values and CFTR mutations and compared the diagnostic characteristics of Asian to non-Asian patients with CF. RESULTS: Asian ...
Molecular surveillance of Plasmodium falciparum resistance to artemisinin-based combination therapies in the Democratic Republic of Congo.
Combination Gene Dosage Genetic Markers Geography Haplotypes Humans Malaria, Falciparum Mutation Plasmodium falciparum Polymorphism, Genetic Protozoan Proteins Abstract: Malaria is a major public health problem ...
Genetically stable infectious Schmallenberg virus persists in foetal envelopes of pregnant ewes.
foetal envelopes is genetically stable since only a few mutations compared to the inoculum were found. This supports the hypothesis that persisting virus could start the infection of new hosts. Finally, ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
(480 000 new cases), impeding the treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations ...
Attenuation of RNA viruses by redirecting their evolution in sequence space.
Darby Canine Kidney Cells Orthomyxoviridae Infections Point Mutation virulence Abstract: RNA viruses pose serious threats to human health. Their success relies on their capacity to generate genetic ...