Search results - 213 results
Development of a data-intensive centralized system for surveillance and outbreak investigation of bacterial pathogens using whole-genome sequencing
(Neisseria meningitidis, Shiga toxin-producing Escherichia coli, and Mycobacterium tuberculosis) to provide a more efficient and powerful alternative to the conventional molecular biology-based methods. ...
Retrospective evaluation of routine whole genome sequencing of Mycobacterium tuberculosis at the Belgian National Reference Center, 2019.
Publication Type: Peer reviewed scientific article Authors: Karine Soetaert; Pieter-Jan Ceyssens; Samira Boarbi; Bert Bogaerts; Thomas Delcourt; Kevin Vanneste; Sigrid C.J. De Keersmaecker; Nancy Roosens; Alexandra Vodolazkaia; Marina Mukovnikova; Vanessa ...
In-vivo expressed Mycobacterium tuberculosis antigens recognised in three mouse strains after infection and BCG vaccination.
directed against Mycobacterium tuberculosis (Mtb) proteins expressed throughout the Mtb infection-cycle. Human Mtb antigen-discovery screens identified antigens encoded by Mtb-genes highly expressed during ...
A Bioinformatics Whole-Genome Sequencing Workflow for Clinical Mycobacterium tuberculosis Complex Isolate Analysis, Validated Using a Reference Collection Extensively Characterized with Conventional Methods and In Silico Approaches
Keersmaecker; Nancy Roosens; Marchal, Kathleen; Vanessa Mathys; Kevin Vanneste Source: J Clin Microbiol (2021) Keywords: Antimicrobial resistance Mycobacterium tuberculosis national reference center public health ...
Use of a Whole Genome Sequencing-based approach for Mycobacterium tuberculosis surveillance in Europe in 2017-2019: an ECDC pilot study.
Publication Type: Peer reviewed scientific article Authors: Elisa Tagliani; Anthony, Richard; Thomas A Kohl; Albert de Neeling; Vlad Nikolayevskyy; Csaba Ködmön; Florian P Maurer; Stefan Niemann; Dick van Soolingen; Marieke J van der Werf; Daniela Maria C ...
Recurrent tuberculosis in a young child
A young child, 19 months of age, presented with a second episode of tuberculosis after full recovery from initial tuberculosis disease 6 months earlier. Mycobacterium tuberculosis strains isolated from both ...
Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.
Publication Type: Peer reviewed scientific article Authors: Martin Hunt; Bradley, Phelim; Lapierre, Simon Grandjean; Simon Heys; Mark Thomsit; Michael B Hall; Kerri M Malone; Penelope Wintringer; Timothy M Walker; Daniela M Cirillo; Iñaki Comas; Maha R Fa ...
In vitro activity of bedaquiline against slow-growing nontuberculous mycobacteria.
concentration (MBC). The MIC of BDQ against 17 clinical isolates including Mycobacterium avium, Mycobacterium intracellulare, Mycobacterium chimaera, Mycobacterium kansasii and Mycobacterium simiae species was ...
Transcriptional profiling of a laboratory and clinical Mycobacterium tuberculosis strain suggests respiratory poisoning upon exposure to delamanid
Source: Tuberculosis, Volume 117 (2019) Keywords: Delamanid Mycobacterium tuberculosis RNA sequencing Transciptomics Abstract: Tuberculosis (TB) is the most deadly infectious disease worldwide. To reduce TB ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
microbes and vectors, Issue Institute Pasteur, Paris, France (2018) Keywords: Mycobacterium tuberculosis; antimicrobial resistance; diagnostics Abstract: To counter the long turnaround time of standard ...