Search results - 142 results
RE-Place: a project to collect the available Belgian expertise on New Approach Methodologies in one central database
Publication Type: Scientific poster, presentation or proceeding Authors: Mieke Van Mulders; N. Liodo Missigba; Birgit Mertens; V Rogiers Source: Beltox/IC-3Rs/Invitrom Scientific Meeting, Brussels (Belgim) (2019) Service: Évaluation des risques et de l&# ...
Validation of a Bioinformatics Workflow for Routine Analysis of Whole-Genome Sequencing Data and Related Challenges for Pathogen Typing in a European National Reference Center: as a Proof-of-Concept.
to replace conventionally employed molecular typing methods for microbial isolates in a representative small-scale laboratory, using the pathogen as a proof-of-concept. We adapted several classically ...
RE-Place: a database compiling New Approach Methodologies
Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens; Mieke Van Mulders; N. Liodo Missigba; V. Rogiers Source: Research Day, Issue University of Antwerp, Antwerp, Belgium (2019) Service: Évaluation des risques et de l&# ...
RE-PLACE: an ambitious project to collect animal-free methodologies in one central database
Publication Type: Scientific poster, presentation or proceeding Authors: V Rogiers; Mieke Van Mulders; N. Liodo Missigba; Birgit Mertens Source: BCLAS, Issue BCLAS, Blankenberge, Belgium (2019) Service: Évaluation des risques et de l'impact sur la s ...
RE-Place: a database compiling New Approach Methodologies
Publication Type: Scientific poster, presentation or proceeding Authors: Birgit Mertens; Mieke Van Mulders; N. Liodo Missigba; V. Rogiers Source: Animals in research, no unless, Issue KU Leuven, Leuven, Belgium (2019) Service: Évaluation des risques et d ...
Development of a real-time PCR method for the genoserotyping of Salmonella Paratyphi B variant Java.
reaching an accuracy, compared with the classical methods, of 98% for serotyping by slide agglutination and 100% for replacement of the biochemical test. The developed real-time PCR permits to save time and ...
Prioritizing substances of genotoxic concern for in-depth safety evaluation using non-animal approaches: The example of food contact materials.
testing, such strategies should respect the 3R principles (Replacement, Reduction, Refinement). In the present study, a strategy based on non-animal approaches was developed to prioritize non-evaluated ...
Black aspergilli: A remaining challenge in fungal taxonomy?
up to clade level in the clinical lab. Our results indicate that MALDI- TOF MS can be a powerful tool to replace classical morphology. Health Topics: Culture collection Cultuurcollectie Collection de ...
Seasonal Genetic Drift of Human Influenza A Virus Quasispecies Revealed by Deep Sequencing
Werf Source: Frontiers in Microbiology, Volume 9 (2018) Abstract: After a pandemic wave in 2009 following their introduction in the human population, the H1N1 pdm09 viruses replaced the previously ...
RE-Place: centralizing information on alternative methods to animal testing to promote knowledge sharing
Database in chemico In silico in vitro new approach methodologies replacement Health Topics: Health and environment Santé et environnement Gezondheid en milieu Service: Évaluation des risques et de ...