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A case of convergent evolution: Several viral and bacterial pathogens hijack RSK kinases through a common linear motif.
factor 2 alpha kinase 2 (EIF2AK2 or PKR) and stress granule formation. Strikingly, ORF45 protein of Kaposi’s sarcoma-associated herpesvirus (KSHV) and YopM protein of use the same peptide motif as L to ...
Development and validation of a targeted LC-MS/MS quantitation method to monitor cell culture expression of tetanus neurotoxin during vaccine production
physical stress conditions applied during bacterial culture was also monitored. This work has been funded by the EU / EFPIA /Innovative Medicines Initiative 2 Joint Undertaking, termed the VAC2VAC project ...
(Non-)Sense of Milk Testing in Small Ruminant Lentivirus Control Programs in Goats. Comparative Analysis of Antibody Detection and Molecular Diagnosis in Blood and Milk.
Abstract: Small ruminant lentivirus (SRLV) control programs are mainly based on diagnostic tests performed on blood samples collected from sheep and goats. Since blood sampling is costly and stressful for the ...
Accelerating vaccine manufacturing development through model-based approaches: current advances and future opportunities
well-defined design spaces, ultimately leading to accelerated vaccine development and improved product quality. The authors stress the significance of an integrated modeling platform for vaccine manufacturing, ...