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Résultats de la recherche - 193 results

Targeted Chromosomal Barcoding Establishes Direct Genotype-Phenotype Associations for Antibiotic Resistance in Mycobacterium abscessus.

Gonzalo-Asensio, Jesús Source: Microbiol Spectr (2023) Abstract: A bedaquiline-resistant Mycobacterium abscessus isolate was sequenced, and a candidate mutation in the gene was identified as responsible for the ...

Development of Digital Droplet PCR Targeting the Influenza H3N2 Oseltamivir-Resistant E119V Mutation and Its Performance through the Use of Reverse Genetics Mutants.

a mutation such as E119V- NA is known, highly sensitive PCR-based genotypic assays can be used to identify the prevalence of such mutant influenza viruses in clinical samples. In this study, based on an ...

Development of a Droplet Digital PCR to Monitor SARS-CoV-2 Omicron Variant BA.2 in Wastewater Samples

Roosens Source: Microorganisms, Volume 11, Issue 3 (2023) Keywords: SARS-CoV-2; omicron; VOC; mutation; RT-ddPCR; variant detection; wastewater surveillance Abstract: Wastewater-based surveillance can be ...

Development of Digital Droplet PCR Targeting the Influenza H3N2 Oseltamivir-Resistant E119V Mutation and Its Performance through the Use of Reverse Genetics Mutants

Publication Type: Peer reviewed scientific article Authors: Laura Van Poelvoorde *; François Dufrasne *; Steven Van Gucht *; Xavier Saelens; Nancy Roosens * Source: Current Issues in Molecular Biology, Volume 45, Issue 3 (2023) Health Topics:  Health and ...

First Belgian Report of Ertapenem Resistance in an ST11 Klebsiella Pneumoniae Strain Isolated from a Dog Carrying blaSCO-1 and blaDHA-1 Combined with Permeability Defects

the presence of  blaSCO-1  and  blaDHA-1, combined with permeability defects caused by point mutations in an outer membrane porin (OmpK37). The presence of the  blaSCO-1  gene on a conjugative IncFIB(K) ...

PRECISION: the Belgian molecular profiling program of metastatic cancer for clinical decision and treatment assignment.

provide access to a targeted drug for patients whose tumors harbor actionable mutations in case the matched drug is not available through reimbursement or clinical trials in Belgium. Health Topics:  Kanker ...

Whole-Genome Sequence Approach and Phylogenomic Stratification Improve the Association Analysis of Mutations With Patient Data in Influenza Surveillance.

mainly focused on the hemagglutinin gene. Whole-genome sequencing (WGS) enables tracking mutations across all influenza segments allowing a better understanding of the epidemiological effects of intra- and ...

In Silico Methods for Chromosome Damage.

Keywords: Chromosome Aberrations Chromosomes DNA Damage Humans Mutagenicity Tests Mutagens Mutation Abstract: Due to the link with serious adverse health effects, genotoxicity is an important toxicological ...

An alarming high prevalence of resistance-associated mutations to macrolides and fluoroquinolones in Mycoplasma genitalium in Belgium: results from samples collected between 2015 and 2018ObjectivesMethodsResultsConclusion

Publication Type: Peer reviewed scientific article Authors: Irith De Baetselier; Chris Kenyon; Wim Vanden Berghe; Hilde Smet; Kristien Wouters; Dorien Van den Bossche; Vuylsteke, Bea; Tania Crucitti Source: Sexually Transmitted Infections, Volume 97, Issu ...

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