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Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.
genotoxicity in an testing battery, and mode of action studies (i.e., genome-wide RNA interference library screening and metabolomics). Among the nucleoside analogues, analogue was curative in mouse models with ...
Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals.
* Source: Chem Res Toxicol, Volume 37, Issue 3 (2024) Keywords: Animals Biomarkers Cell Line DNA Damage Gene Expression Profiling Humans Transcriptome Abstract: To modernize genotoxicity assessment and reduce ...