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transcriptase

Zoekresultaten - 24 results

Physicochemical characterization and genotoxicity assessment of nanomaterials using new approach methodologies

containing a fraction of nanoparticles [4], as well as new innovative NAM s such as the transcriptomics-based biomarker, called GENOMARK. This NAM uses prediction models to classify analyzed materials as ...

Unraveling clonal CD8 T cell expansion and identification of essential factors in γ-herpesvirus-induced lymphomagenesis.

global phenotypic changes in circulating CD8 T cells after experimental infection of calves. T cell receptor repertoire together with transcriptomics and epigenomics analyses demonstrated an oligoclonal ...

Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals.

* Source: Chem Res Toxicol, Volume 37, Issue 3 (2024) Keywords: Animals Biomarkers Cell Line DNA Damage Gene Expression Profiling Humans Transcriptome Abstract: To modernize genotoxicity assessment and reduce ...

A Transcriptomic Biomarker to Classify Chemical-Induced Histone Deacetylase Inhibition in Human HepaRGTM Cells

Science Forum, Ottawa, Canada (2024) Keywords: HepaRG cells histone deacetylase inhibition transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu ...

The GENOMARK transcriptomic biomarker: a new approach methodology for genotoxicity (Qualitative and quantitative aspects)

Source: Joint 3R Symposium 2023 (2023) Keywords: genotoxicity NAMs transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des ...

Unlocking the power of transcriptomic biomarkers in qualitative and quantitative genotoxicity assessment of chemicals

Source: 57th Congress of the European Societies of Toxicology (Eurotox 2023), Ljubljana, Slovenia (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health ...

Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.

Issue 2 (2023) Keywords: Algorithms Animals Biomarkers DNA Damage Gene Expression Profiling Humans Supervised Machine Learning Abstract: Transcriptomics-based biomarkers are promising new approach ...

The GENOMARK transcriptomic biomarker demonstrates a high predictivity for genotoxic hazards and utility in potency ranking in human HepaRGTM cells

Source: EEMGS meeting, Malaga, Spain (2023) Keywords: benchmark dose modelling genotoxicity potency ranking transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid ...

The GENOMARK biomarker inhuman HepaRGTM cells: a new approach methodology for genotoxicity assessment

SaferWorldByDesign webinar, Online (2023) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation des risques et de ...

GENOMARK, a promising new approach methodology for genotoxicity testing in the cosmetic industry

International cosmetic congress, Antalya, Turkey (2022) Keywords: genotoxicity NAM transcriptomic biomarker Health Topics:  Health and environment Santé et environnement Gezondheid en milieu Service:  Évaluation ...

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