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Zoekresultaten - 1589 results

The GEN-ERA toolbox: unified and reproducible workflows for research in microbial genomics

command and are available on the GEN- ERA GitHub repository (https: //github.com/Lcornet/ GENERA). All the workflows are based on Singularity containers to increase reproducibility. Testing: The toolbox was ...

Speeding up drug susceptibility testing in Mycobacterium tuberculosis using RNA biomarkers

testing [pDST] for Mycobacterium tuberculosis [TB], we introduce TRAC eR- TB, a test that infers drug resistance from antibiotic-specific mRNA biomarkers. Methods To develop TRAC eR- TB, target genes were ...

Un nouvel outil pour les maladies rares: une base de données répertoriant les tests génétiques réalisés en Belgique

Inscrit dans le Plan belge pour les maladies rares et se référant à la gestion de la qualité dans les Centres belges de génétique médicale (CGM) officiellement désignés, la base de données des tests ...

Implementation of METROFOOD services in the Belgium node

tested for performance and high-quality service provision, and (e) sufficiently valorized. METROFOOD- FED. BE services will be made available for Open Access to external target users and stakeholders via ...

Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.

identified following screening against the most relevant trypanosome species. Selected hit compounds were extensively tested for metabolic stability, potency in mouse models for the various species, ...

Speeding up drug susceptibility testing in Mycobacterium tuberculosis using RNA biomarkers

Publication Type: Peer reviewed scientific article Authors: Amandine Sury*; Margo Maex; Baulard, Alain; Bhattacharyya, Roby P.; Stéphanie Depickère; Hung, Deborah T.; Cos, Paul; Sayes, Fadel; Frigui, Wafa; Brosch, Roland; Vanessa Mathys; Streicher, Elizab ...

Pitch Presentation 'RE-Place'

RIVM, Issue ZonMW & RIVM, Den Haag, The Netherlands (2024) Keywords: 3R animal testing Database Knowledge sharing NAMs new approach methodologies replacement Service:  Risques chimiques et physiques ...

Advanced Analysis of Biopharmaceuticals: Endotoxin content & Sterility testing

Publication Type: Scientific poster, presentation or proceeding Authors: Tesolin, L. Source: African Medicines Regulatory Harmonization (AMRH) 5th Continental GMP Training Workshop: A focus on Vaccines and other Biologics 9-12 December, 2024, virtual Webi ...

Advancing the Replacement of animal testing in Toxicology via the RE-Place platform

non-clinical safety testing strategies for the development of human medicinal products’, Issue BelTox & BEMS, Ghent, Belgium (2024) Keywords: 3Rs Database Knowledge sharing NAMs new approach methodologies ...

Physicochemical characterization and genotoxicity assessment of nanomaterials using new approach methodologies

assessment [1,2]. Currently, hazard and risk assessment still heavily relies on conventional animal testing.  Use of new approach methodologies (NAM s) can fill certain data gaps and complement the available safety ...

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