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Immunovirological and environmental screening reveals actionable risk factors for fatal COVID-19 during post-vaccination nursing home outbreaksAbstract
Bruno; Hellemans, Jorn; Vanhee, Merijn; Reynders, Marijke; Boulouffe, Caroline; Djiena, Achille; Broucke, Caroline; Boudewijn Catry; Lagrou, Katrien; Van Ranst, Marc; Neyts, Johan; Baele, Guy; Maes, Piet; ...
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
Cameron, Craig E; Verdaguer, Nuria; Neyts, Johan; van Kuppeveld, Frank J M Source: PLoS Pathog, Volume 11, Issue 3, p.e1004733 (2015) Keywords: Animals Antiviral Agents Binding Sites Cardiovirus Chlorocebus ...
A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.
King, Donald P; Neyts, Johan; Kris De Clercq Source: Biochem Biophys Res Commun, Volume 455, Issue 3-4, p.378-81 (2014) Keywords: Animals Antiviral Agents Benzimidazoles Cell Line Cell Survival ...
Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.
Neyts, Johan; Paeshuyse, Jan Source: Antiviral Res, Volume 106, p.71-9 (2014) Keywords: Animals Antiviral Agents Benzimidazoles Cattle Cell Line Classical swine fever virus Diarrhea Virus 1, Bovine Viral ...
In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks.
Publication Type: Peer reviewed scientific article Authors: Osiceanu, Ana-Maria; Murao, Lyre Espada; Kollanur, Denny; Swinnen, Jan; Annebel De Vleeschauwer; David Lefebvre; Kris De Clercq; Neyts, ...
Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases.
Lefebvre, David; Lanke, Kjerstin H W; Kris De Clercq; Hilgenfeld, Rolf; Neyts, Johan; van Kuppeveld, Frank J M Source: Antiviral Res, Volume 103, p.17-24 (2014) Keywords: 3C Viral Proteases Animals Antiviral ...
Intra-host variation structure of classical swine fever virus NS5B in relation to antiviral therapy.
Publication Type: Peer reviewed scientific article Authors: Andy Haegeman; Vrancken, Robert; Neyts, Johan; F. Koenen Source: Antiviral Res, Volume 98, Issue 2, p.266-72 (2013) Keywords: Amino Acid ...
Diagnostic performance and application of two commercial cell viability assays in foot-and-mouth disease research.
Publication Type: Peer reviewed scientific article Authors: Willems, Tom; David Lefebvre; Neyts, Johan; Kris De Clercq Source: J Virol Methods, Volume 173, Issue 1, p.108-14 (2011) Keywords: Animals ...
Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor.
Marie-Frédérique; Neyts, Johan; F. Koenen Source: J Gen Virol, Volume 90, Issue Pt 6, p.1335-42 (2009) Keywords: Administration, Oral Animals Antiviral Agents Classical Swine Fever Classical swine fever virus ...
A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase.
Teulade, Jean-Claude; Herdewijn, Piet; Puerstinger, Gerhard; F. Koenen; Pierre Kerkhofs; Baraldi, Pier Giovanni; Neyts, Johan Source: Antiviral Res, Volume 82, Issue 3, p.141-7 (2009) Keywords: Amino Acid ...