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Speeding up drug susceptibility testing in Mycobacterium tuberculosis using RNA biomarkers
underestimated due to the inclusion of isolates harbouring uncharacterised mutations. TRAC eR- TB demonstrated 100% concordance with MGIT for drugs with reliable MGIT outcomes (moxifloxacin and isoniazid). ...
Assessment of receptor-mediated activity (AhR and ERα), mutagenicity, and teratogenicity of metal shredder wastes in Wallonia, Belgium.
the bacterial reverse gene mutation test using the Salmonella typhimurium TA98 and TA100 strains. Except for the sludge sample (site 3), all samples induced a mutagenic response in the TA98 strain (± ...
Unraveling clonal CD8 T cell expansion and identification of essential factors in γ-herpesvirus-induced lymphomagenesis.
rendered AlHV-1 unable to induce MCF. Furthermore, A10 was phosphorylated in T lymphocytes in vitro and affected T cell signaling. Finally, while AlHV-1 mutants expressing mutated forms of A10 devoid of ITAM ...
High pathogenic avian influenza A(H5) viruses of clade 2.3.4.4b in Europe-Why trends of virus evolution are more difficult to predict.
reassortment, its jumps to a progressively wider number of host species, including mammals, and the rapid acquisition of adaptive mutations make the trend of virus evolution and spread difficult to predict in ...
Azithromycin resistance in Escherichia coli and Salmonella from food-producing animals and meat in Europe.
1007 E. coli [165 azithromycin resistant (MIC > 16 mg/L)] and 269 Salmonella [29 azithromycin resistant (MIC > 16 mg/L)] were screened for acquired macrolide resistance genes and mutations in ...
be.Prepared: Transition to timely genomic resistance surveillance
helping to identify mutations, track new variants, and support vaccine development. Building on this experience, there is now a clear need for a flexible system that can be used to monitor a wide range of ...
The landscape of drug resistance in Plasmodium falciparum malaria in the Democratic Republic of Congo: a mapping systematic review
Source: Trop Med Health, Volume 51, Issue 1 (2023) Keywords: Antimalarial drug resistance Democratic Republic of Congo Malaria Molecular markers of drug resistance mutations Abstract: CONTEXT: The ...
Whole-Genome Sequencing-Based Screening of MRSA in Patients and Healthcare Workers in Public Hospitals in Benin.
From this collection, 27 high-quality WGS datasets were obtained, which carried numerous genes and mutations associated with antimicrobial resistance. The gene was detected in all the sequenced isolates. ...
Whole-Genome Sequence Approach and Phylogenomic Stratification Improve the Association Analysis of Mutations With Patient Data in Influenza Surveillance
Publication Type: Peer reviewed scientific article Authors: Laura Van Poelvoorde; Kevin Vanneste; Sigrid C.J. De Keersmaecker; Isabelle Thomas; Nina Van Goethem; Steven Van Gucht; Xavier Saelens; Nancy Roosens Source: Frontiers in Microbiology, Volume 13 ...
Virological surveillance of influenza in Belgium, season 2019-2020
previous seasons. None of the analyzed strains presented mutations known to be associated to resistance to antivirals neuraminidase inhibitors (Oseltamivir et Zanamivir). Health Topics: Health and disease monitoring ...