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Development and validation of a TaqMan probe-based real-time PCR method for the differentiation of wild type lumpy skin disease virus from vaccine virus strains.
targeting the GPCR gene was developed and validated, for the concurrent detection and differentiation of wild type and vaccine Lumpy skin disease virus (LSDV) strains. The method was evaluated in three ...
Differential modulations of striatal tyrosine hydroxylase and dopamine metabolism by cannabinoid agonists as evidence for functional selectivity in vivo.
exposure expression Functional G protein GPCR Increase IS metabolism metabolites ON rats Reduction regulation report response structure System Transmission trend Tyrosine hydroxylase Abstract: It is ...
Neuropeptide receptors as possible targets for development of insect pest control agents4385
receptors belong to two distinct categories of signal transducing proteins, i.e., heptahelical or G protein-coupled receptors (7TM, GPCR) and single transmembrane containing receptors. An increasing amount ...
KLHL12-mediated ubiquitination of the dopamine D4 receptor does not target the receptor for degradation.
degradation of mature receptors. Moreover, our data reveal that D4 receptors do not undergo agonist-promoted ubiquitination or degradation, in contrast to many other G-protein-coupled receptors (GPCR s) ...
CC chemokine ligand-2 synergizes with the nonchemokine G protein-coupled receptor ligand fMLP in monocyte chemotaxis, and it cooperates with the TLR ligand LPS via induction of CXCL8
basis of the discovery of synergy between chemokines for neutrophil attraction, we extend here this phenomenon between the chemokine MCP-1/ CCL2 and the GPCR ligand fMLP or the TLR4 agonist LPS on ...
Nutrient sensing systems for rapid activation of the protein kinase A pathway in yeast.
and sucrose activate cAMP synthesis through a G-protein-coupled receptor system, consisting of the GPCR Gpr1, the Galpha protein Gpa2 and its RGS protein Rgs2. Glucose is also sensed intracellularly ...
Phenolamine-dependent adenylyl cyclase activation in Drosophila Schneider 2 cells481
are often employed as host cells for non-lytic, stable expression and functional characterization of mammalian and insect G-protein-coupled receptors (GPCR s), such as biogenic amine receptors. In order ...