Search results - 47 results

Anti-mycobacterial activity of 1,3-diaryltriazenes.

Macrophages mice Microbial Sensitivity Tests Molecular Structure Mycobacterium avium Mycobacterium bovis Mycobacterium ulcerans Structure-Activity Relationship Triazenes Abstract: The rapid generation and ...

2,4-Dialkyl-8,9,10,11-tetrahydrobenzo[g]pyrimido[4,5-c]isoquinoline-1,3,7,12(2H,4H)-tetraones as new leads against Mycobacterium tuberculosis.

dialkyltetrahydrobenzo[g]pyrimido [4,5-c]isoquinolinetetraones were designed and synthesised. The compounds were submitted to a biological evaluation in which the activity against M.tb H37R v(lux) was observed, as well as the acute ...

Laboratory diagnosis of paediatric tuberculosis in the European Union/European Economic Area: analysis of routine laboratory data, 2007 to 201136508

VALIDATION values Abstract: Laboratory confirmation of paediatric tuberculosis (TB) is frequently lacking. We reviewed the range of routine laboratory tests and their performance in different biological ...

Biological evaluation of diazene derivatives as anti-tubercular compounds.

substituted diazenecarboxamides, three carbamoyldiazenecarboxylates and four diazene-1,2-dicarboxamides was synthesized in a straightforward manner followed by a biological evaluation of the compounds. We ...

The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases.

IntAct database at EMBL- EBI and are merged with the existing IntAct dataset. Both IntAct and MINT are active contributors to the IME x consortium (http://www.imexconsortium.org). Full text language:  ...

Comparing the endocrine activity (ER, AR, Trb and PPARy) of BPA and other bisphenols

des denrées alimentaires Voedselcontactmaterialen Bisphénol A Bisfenol A Bisphenol A Full text language:  English Category:  C1 FOS Classification:  1.6 Biological sciences ...

In vitro model to study the endocrine disrupting activity of migration products from plastic food contact materials

luciferase gene, as a reporter gene, and a DNA responsive element specific to the human oestrogen receptor. The biological activity of a chemical compound is monitored by the measurement of light emitted by ...

Urinary nicotine metabolites: usefulness as biomarkers of smoking status

Tratnik,J.S.; Joris Van Loco; Koen De Cremer; K. Jones Source: International Symposium on biological monitoring in occupational and environmental health, Issue Kate Jones,Health and Safety Laboratory,UK, ...

Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect.

Transcriptional Activation Abstract: Recently the environmental obesogen hypothesis has been formulated, proposing a role for endocrine disrupting compounds (EDC s) in the development of obesity. To evaluate this ...

Routinely-collected general practice data from the electronic patient record and general practitioner active electronic questioning method: A comparative study

investigated for 10,307 Belgian patients 10 healthcare conditions using clinical and biological parameters (cholesterol, blood pressure, and body mass index), diagnoses (hypertension, diabetes, and personal past ...

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