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Effects of long-term exposure to 50 Hz magnetic fields on cell viability, genetic damage, and sensitivity to mutagen-induced damage.

sensitivity to mutagen-induced damage were evaluated using the alkaline comet assay and the cytokinesis block micronucleus assay. The results showed that long-term exposure up to 96h to 50 Hz  MF at all tested ...

Impact of experimental design factors on the potency of genotoxicants in in vitro test

(EMS)] in the in vitro micronucleus (MN) assay and comet assay (CA). Both compounds were tested in the two assays using two cell types (i.e. CHO- K1 and TK6 cells). To evaluate the effect of exposure ...

New QSAR models to predict chromosome damaging potential based on the in vivo micronucleus test

structural and numerical chromosome aberrations. Even fewer of these are based on the preferred testing method for this endpoint, i.e. the micronucleus test. For the present work, in vivo micronucleus test ...

In vitro 50 Hz magnetic field long-term exposure: Cytogenetic tests on human lymphoblastoid TK6 cells and validation of the test environment

Feipel; Birgit Mertens Source: MethodsX, Volume 7 (2020) Keywords: Background magnetic field Comet Assay Extremely low-frequency magnetic fields Micronucleus test Shielding system Abstract: Potential health ...

In vitro toxicity, genotoxicity and antigenotoxicity of Nigella sativa extracts from different geographic locations

micronucleus and comet tests in human C3A cells to investigate the in vitro cytotoxicity, genotoxicity and antigenotoxicity of aqueous seed extracts of this plant originating from three different regions ...

Genotoxic evaluation of the liquids present in electronic cigarettes

animal-free approaches. In addition, the applicability of the Ames test and the in vitro micronucleus test to evaluate the genotoxic potential of e-liquids mixtures was investigated. [Methods]  The study was ...

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