Search results - 11 results
The strategic change of the API fingerprint programme: from verification of authenticity of API sources to identifying potential quality issues
recognition techniques would be applied first to group the different manufacturers and select those producers for which deviating samples or inconsistencies are observed. In a second step, pattern recognition ...
Multidimensional chromatographic fingerprinting combined with chemometrics for the identification of regulated plants in suspicious plant food supplements
× time points) were used for selection of orthogonal wavelengths by conducting a correlation analysis. After preparation of triturations, recording of the fingerprints and creation of datasets (corrected ...
COMBINATION OF CHEMOMETRICS AND MULTIDIMENSIONAL FINGERPRINTING FOR DETECTION OF REGULATED PLANTS IN PLANT FOOD SUPPLEMENTS
method was developed using ultra-high performance liquid chromatography with diode array detector (DAD). Furthermore, selection of orthogonal wavelengths was made to extract maximum information from the ...
Multidimensional Chromatographic Fingerprinting Combined with Chemometrics for the Identification of Regulated Plants in Suspicious Plant Food Supplements.
the chromatogram, a multidimensional fingerprint (absorbance × wavelength × retention time) was considered. This was achieved by selecting several wavelengths through a correlation analysis. The data ...
Multidimensional Fingerprint Development for the Detection of Tribulus terrestris in Plant Food Supplements
fingerprinting at different wavelengths for identification of Tribulus terrestris in plant food supplements. A specific, selective and fast fingerprinting method for Tribulus (reference material obtained from the ...
GEONs API fingerprint project: Selection of analytical techniques for clustering of sildenafil citrate API samples
future with the selected techniques in order to link the sample to a manufacturer or demonstrate the absence of such link. If the sample cannot be attributed to one of the manufacturers, further analysis ...
Characterization and risk identification of falsified medicines and adulterated dietary supplements
selectivity and specificity for the detection of targeted plants in mixtures. It stands to reason that collaborations on these topics would be beneficial for both the European and the Chinese policy makers to ...
The occurrence of non-anatomical therapeutic chemical-international nonproprietary name molecules in suspected illegal or illegally traded health products in Europe: A retrospective and prospective study.
molecules of biological origin, that is, research peptides, representing the second most reported category in this study. Furthermore, the study also clearly shows the increasing popularity of Selective ...
Development and validation of chromatographic methods for screening and subsequent quantification of suspected illegal antimicrobial drugs encountered on the Belgian market.
agents, 1 antifungal agent and 1 beta-lactamase inhibitor, covering eleven different antibacterial classes, were selected. The UHPLC- MS screening method with gradient elution is able to selectively detect ...
Analysis of illegal peptide drugs via HILIC-DAD-MS.
five different HILIC columns were selected and screened for their chromatographic performance. Among those columns, the ZIC HILIC column showed the best performance under the tested screening conditions ...