Search results - 50 results
Safety assessment of the substance 2,2'-oxydiethylamine for use in plastic food contact materials.
temperature. Specific migration of 2,2’-oxydiethylamine was tested from a polyamide film in water and was below the limit of quantification (LOQ) of 0.015 mg/kg. Migration of impurities has been estimated ...
Assessment of receptor-mediated activity (AhR and ERα), mutagenicity, and teratogenicity of metal shredder wastes in Wallonia, Belgium.
the bacterial reverse gene mutation test using the Salmonella typhimurium TA98 and TA100 strains. Except for the sludge sample (site 3), all samples induced a mutagenic response in the TA98 strain (± ...
Towards a more effective REACH legislation in protecting human health.
several years leading to uncertainties for both producers and end users. A first proposed improvement is the implementation of independent toxicity testing, to assure objectivity, transparency, and check ...
Linking nanomaterial-induced mitochondrial dysfunction to existing adverse outcome pathways for chemicals.
(AOP) framework plays a crucial role in the paradigm shift of toxicity testing towards the development and use of new approach methodologies. AOP s developed for chemicals are in theory applicable to ...
Regulatory safety assessment of nanoparticles for the food chain in Europe
Keywords: Integrated approaches to testing and assessment (IATA) nanomaterial particulate material Physicochemical characterisation Risk Assessment Toxicity testing Abstract: Background The risk assessment of ...
Multidimensional Fingerprint Development for the Detection of Tribulus terrestris in Plant Food Supplements
properties. According to the Belgian Royal Decree of 1997, Tribulus is a regulated plant when used in plant food supplements. The dangers of self-medication and toxicity of such plant supplements is heightened ...
Safety assessment of titanium dioxide (E171) as a food additive.
Studies on general and organ toxicity did not indicate adverse effects with either E 171 up to a dose of 1,000 mg/kg body weight (bw) per day or with TiO NP s (> 30 nm) up to the highest dose tested of ...
Safety assessment of titanium dioxide (E171) as a food additive
dose tested of 100 mg/kg bw per day. No effects on reproductive and developmental toxicity were observed up to a dose of 1,000 mg E 171/kg bw per day, the highest dose tested in the EOGRT study. However, ...
Identifying nanodescriptors to predict the toxicity of nanomaterials: a case study on titanium dioxide
8, Issue 2 (2021) Abstract: Since the evaluation of nanomaterial (NM) hazards by animal testing is expensive, time-consuming and critical from an ethical point of view, much interest is being given to ...
Ecotoxicity profile of heavily contaminated surface water of two rivers in Tunisia
areas. Combining chemical and biological approaches, allowed the detection of water ecotoxicity in testing organisms and the identification of possible contributors to the toxicity observed in these ...