Search results - 20 results
Unraveling clonal CD8 T cell expansion and identification of essential factors in γ-herpesvirus-induced lymphomagenesis.
cattle results in the induction of an acute and lethal peripheral T cell lymphoma-like disease (PTCL), named malignant catarrhal fever (MCF). Our previous findings demonstrated an essential role for viral ...
Differential infection behavior of African swine fever virus (ASFV) genotype I and II in the upper respiratory tract.
particularly in animals with acute ASF. Our study addresses the understudied role of nasal mucosa in ASFV infection, using a nasal explant model. The explants remained viable and revealed a discernible ASFV ...
The African swine fever virus isolate Belgium 2018/1 shows high virulence in European wild boar.
sub-adult wild boar to further characterize the virus and its distribution in different tissues. After oronasal inoculation with the virus strain ‘Belgium 2018/1’, all animals developed an acute and severe ...
Clinical problems due to encephalomyocarditis virus infections in two pig herds.
12 days old were dying acutely whereas in herd B, piglets at the end of the nursery period (8-10 weeks) were showing identical problems. A presumptive diagnosis of encephalomyocarditis virus infection was ...
Coxiella burnetii, agent de la fièvre Q
often goes underdiagnosed because the main manifestation of its acute form is a general self-limiting flu-like syndrome. The Dutch epidemics renewed attention to this disease, which was less considered ...
Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice.
no longer detected in 13 of 15 treated mice. All eight untreated mice suffered from an acute generalized disease and were euthanized for ethical reasons on average at 4 dpi. These results illustrate ...
Experimental Schmallenberg virus infection of pigs.
(2014) Keywords: Animals Antibodies, Neutralizing Antibodies, Viral Bunyaviridae Infections Feces Orthobunyavirus Swine Abstract: Schmallenberg virus (SBV) is a newly emerged virus responsible for an acute ...
An essential role for γ-herpesvirus latency-associated nuclear antigen homolog in an acute lymphoproliferative disease of cattle.
Kerkhofs; Vanderplasschen, Alain; Dewals, Benjamin G Source: Proc Natl Acad Sci U S A, Volume 110, Issue 21, p.E1933-42 (2013) Keywords: Acute Disease Animals Antigens, Nuclear Antigens, Viral Cattle ...
CP7_E2alf oral vaccination confers partial protection against early classical swine fever virus challenge and interferes with pathogeny-related cytokine responses.
revealed that both vaccinations attenuated the effects induced by CSFV on production of the pig major acute phase protein (PigMAP), IFN-α, IL-12, IL-10, and TGF-β1 cytokines. By this interference, several ...
Influenza A strain-dependent pathogenesis in fatal H1N1 and H5N1 subtype infections of mice.
viruses evoked diffuse alveolar damage and showed a similar 50% mouse lethal dose and the same peak lung concentration, each had a distinct pathologic signature and caused a different course of acute ...