Search results - 117 results
The Benefits of Whole Genome Sequencing for Foodborne Outbreak Investigation from the Perspective of a National Reference Laboratory in a Smaller Country.
initially. Although some bottlenecks concerning centralized data-sharing, sampling strategies, and perceived costs should be considered, we delivered a proof-of-concept that even in smaller countries, WGS ...
The genome as individual property or common good. Conceptualization of the genome within a citizen forum
showed particular interest in public engagement in genomics. However, most projects focus on expressed values, without exploring the concepts behind them. To understand which uses of genomic information ...
ADVANCE database characterisation and fit for purpose assessment for multi-country studies on the coverage, benefits and risks of pertussis vaccinations.
of concept studies. RESULTS: The databases contained data for a total population of 44 million individuals. Seven databases had recorded doses of vaccines. The pertussis coverage estimates were similar ...
Selection of a Noninvasive Source of Human DNA Envisaging Genotyping Assays in Epidemiological Studies: Urine or Saliva?
Genomic DNA was extracted using commercial kits. Quantitative and qualitative evaluation was done by assessing the yield, the purity, and integrity of the extracted DNA. As a proof-of-concept, genotyping ...
Species Distinction in the Trichophyton rubrum Complex.
species within the complex, molecular, phenotypic, and physiological characteristics were combined to reestablish a natural species concept. Three groups,,, and, could be distinguished based on the sequence ...
Validation of a Bioinformatics Workflow for Routine Analysis of Whole-Genome Sequencing Data and Related Challenges for Pathogen Typing in a European National Reference Center: as a Proof-of-Concept.
to replace conventionally employed molecular typing methods for microbial isolates in a representative small-scale laboratory, using the pathogen as a proof-of-concept. We adapted several classically ...
Detailed Evaluation of Data Analysis Tools for Subtyping of Bacterial Isolates Based on Whole Genome Sequencing: as a Proof of Concept.
Publication Type: Peer reviewed scientific article Authors: Assia Saltykova; Wesley Mattheus; Sophie Bertrand; Nancy Roosens; Marchal, Kathleen; Sigrid C.J. De Keersmaecker Source: Front Microbiol, Volume 10 (2019) Abstract: Whole genome sequencing is inc ...
Measuring disability: a systematic review of the validity and reliability of the Global Activity Limitations Indicator (GALI).
two distinct health concepts, self-rated health and GALI, acted independently and complementary of each other. The one reliability study identified reported a sufficient reliability of GALI. Conclusion: ...
Welfare-Adjusted Life Years (WALY): A novel metric of animal welfare that combines the impacts of impaired welfare and abbreviated lifespan.
lifespan at the time of premature death. To demonstrate the concept, we estimated WALY s for 10 common canine diseases, namely mitral valve disease, dilated cardiomyopathy, chronic kidney disease, diabetes ...
New insights in dermatophyte research.
concepts of zoo- and anthropophily may require revision in some recently redefined species. Many of these questions benefit from international cooperation and exchange of materials. The aim of the ISHAM ...