Search results - 117 results

Assessing the potency of oral polio vaccine kept outside of the cold chain during a national immunization campaign in Chad

cumulative exposure to heat reached levels that may have negatively affected the vaccine’s potency. This study provides proof-of-concept evidence that certain types of OPV remain potent and thus can be kept, ...

The consistency approach for quality control of vaccines- a strategy to improve quality control and implement 3Rs

release concept Congresses Control Development Discussion electronic health Human Humans im implement implementation improve in vivo IS IT method methods need Netherlands ON Order production Quality Quality ...

Fine quantification of avian influenza H5N1 escape mutant quasispecies populations using mutation-specific real-time PCR.

real-time PCR (RT- PCR) tests for the fine quantification of mutations in a background of wild-type sequences. As a proof-of-concept model, we developed mutation-specific RT- PCR tests to quantify antibody ...

A theoretical introduction to "combinatory SYBRGreen qPCR screening", a matrix-based approach for the detection of materials derived from genetically modified plants.

for each method. A theoretical explanation of the different concepts applied in CoSYPS analysis is given (GMO Universe, “Prime number tracing”, matrix/combinatory approach) and documented using the ...

The reduction of CSFV transmission to untreated pigs by the pestivirus inhibitor BPIP: a proof of concept.

swine fever virus (CSFV). We recently demonstrated in a proof of concept study that the molecule has a marked effect on viral replication in CSFV-infected pigs. Here, the effect of antiviral treatment on ...

Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor.

Publication Type: Peer reviewed scientific article Authors: Vrancken, Robert; Andy Haegeman; Paeshuyse, Jan; Puerstinger, Gerhard; Rozenski, Jef; Wright, Matthew; Marylène Tignon; Le Potier, Marie-Frédérique; Neyts, Johan; F. Koenen Source: J Gen Virol, V ...

Synthetic EthR inhibitors boost antituberculous activity of ethionamide36849

& inhibitors Antitubercular Agents article AS Binding Sites chemistry concept conventional culture de DNA-Binding Proteins DRUG Drug Resistance Drug Synergism drug therapy drugs effect effects ...

Immunogenicity of eight dormancy regulon-encoded proteins of Mycobacterium tuberculosis in DNA-vaccinated and tuberculosis-infected mice.

Rv1733c, Rv2031c, and Rv2626c. These findings have implications for proof-of-concept studies in mice mimicking tuberculosis (TB) latency models and their extrapolation to humans for potential new vaccination ...

Delivery of DNA vaccines by agarose hydrogel implants facilitates genetic immunization in cattle.

second experiment extends the same concept with innovative agarose hydrogel implants. These latter implants are cheaper and more convenient than the osmotic pumps or repeated intradermal administrations ...

The Determination of Chemical Elements in FoodMethod Validation for Food Analysis: Concepts and Use of Statistical Techniques

Publication Type: Scientific book or chapter Authors: Caroli, Sergio; Joris Van Loco Source: Applications for Atomic and Mass Spectrometry, John Wiley & Sons, Inc., Issue 6, Hoboken, NJ, USA (2006) ISBN: 9780471687849 Keywords: detection capabilities ...

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