Search results - 18 results
Novel prediction models for genotoxicity based on biomarker genes in human HepaRG™ cells.
DNA microarray profiles of 24 (non-)genotoxic reference chemicals covering different modes of action in metabolically competent human HepaRG™ cells. In the present study, new prediction models for ...
Novel prediction models for genotoxicity based on biomarker genes in human HepaRGTM cells
microarray profiles of 24 (non-)genotoxic reference chemicals covering different modes of action in metabolically competent human HepaRG™ cells. In the present study, new prediction models for genotoxicity ...
DLL4 expression is a prognostic marker and may predict gemcitabine benefit in resected pancreatic cancer.
potential therapeutic target to improve outcome for patients with pancreatic ductal adenocarcinoma (PDAC). METHODS: Using immunohistochemistry (IHC) and tissue microarray (TMA), we assessed the expression ...
Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.
were initially challenged with thirty compounds, genome-wide gene expression was measured with microarrays, and hazard classifiers were built from this training set. Subsequently, each system was ...
Development of a Luminex xTAG® assay for cost-effective multiplex detection of β-lactamases in Gram-negative bacteria.
detect multiple variants of the same allele, and (ii) significantly more cost-effective than commercial microarrays and WGS. The targeted β-lactamases include ESBL s (CTX-M families and subtypes, ESBL and ...
Antimicrobial resistance and population structure of Staphylococcus aureus recovered from pigs farms.
found for ciprofloxacin (61.1%), clindamycin (64.4%), erythromycin (57.8%), kanamycin (43.1%) and gentamicin (45.5%). Microarray analysis showed that most CC398 isolates carried genes encoding resistance ...
Current and new approaches in GMO detection: challenges and solutions
https://www.sciensano.be/en/biblio/current-and-new-approaches-gmo-detection-challenges-and-solutions
detections of multiple GM targets (e.g., PCR capillary gel electrophoresis, microarray, and Luminex), more accurate quantification of GM targets (e.g., digital PCR), or characterization of partially known ...
Whole genome protein microarrays for serum profiling of immunodominant antigens of Bacillus anthracis.
genome protein microarray has been used to identify immunogenic Anthrax proteins (IAP) using sera from groups of donors with (a) confirmed B. anthracis naturally acquired cutaneous infection, (b) confirmed ...
Diversity of antimicrobial resistance and virulence genes in methicillin-resistant non-Staphylococcus aureus staphylococci from veal calves.
virulence genes. Fifty-eight MRNAS were studied by means of DNA-microarray and PCR for detection of antimicrobial resistance and virulence genes. The isolates carried a variety of antimicrobial-resistance ...
Sonic hedgehog and Gli1 expression predict outcome in resected pancreatic adenocarcinoma.
value of four Hh signaling proteins and of the tumor stromal density. EXPERIMENTAL DESIGN: Using tissue microarray and immunohistochemistry, the expression of Shh, Gli1, SMO, and PTCH1 was assessed in 567 ...