Search results - 101 results
In silico methods for chromosome damage
to human health, including for pharmaceuticals. To this extent, a compound’s potential to induce gene mutations as well as chromosome damage needs to be addressed. For chromosome damage, i.e. the ...
Annual Report Belgian Cystic Fibrosis Registry 2018
registry, 18 years ago, 39.0% were adults, and the median age was 14.9 years, showing changes in demographics over the years. 45.8% of the patients are homozygous for the F508 del mutation and 38.0% are F508 ...
Annual Report Belgian Cystic Fibrosis Registry 2017
18 years ago, 39.0% were adults, and the median age was 14.9 years. 46.4% of the patients are homozygous for the F508 del mutation and 39.1% are F508 del heterozygous. The main reasons for diagnosis of ...
Annual report Belgian Cystic Fibrosis Registry 2016
can be compared to the start of the registry 17 years ago when 39.0% were adults with a median age of 14.9 years. 46.7% of the patients are homozygous for the F508 del mutation while 37.0% are F508 del ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
(480 000 new cases), impeding the treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
treatment of infected patients. Current TB drug resistance research is mainly focused on the genomic level, using WGS to search for resistance-causing mutations. However, transcriptional analyses can be ...
Revisiting susceptibility testing in MDR-TB by a standardized quantitative phenotypic assessment in a European multicentre study9
ITALY journal Laboratories LEVEL levels medical method methods Microbial Sensitivity Tests microbiology Mutation Mycobacterium Mycobacterium tuberculosis national Netherlands objectives observed ON ...
Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage20
Medicine microbiology Molecular Molecular biology Molecular Epidemiology Mutation Mycobacterium Mycobacterium tuberculosis national organization parasitology paris pathogen pathology pediatric Peru Phylogeny ...
The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.
barrier to resistance against GPC- N114. By contrast, EMCV, a cardiovirus, rapidly acquired resistance due to mutations in 3Dpol. In vitro polymerase activity assays showed that GPC- N114 i) inhibited the ...
Genotoxicity testing of 3,4,5-trimethylfuran-2(5H)-one, a compound from plant-derived smoke with germination inhibitory activity.
Publication Type: Peer reviewed scientific article Authors: Light, Marnie E; Anthonissen, Roel; Annemarie Maes; Luc Verschaeve; Pošta, Martin; Van Staden, Johannes Source: Mutat Res Genet Toxicol ...