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Validation of TaqMan-Based Assays for Specific Detection and Differentiation of Wild-Type and Neethling Vaccine Strains of LSDV.

able to distinguish Neethling-based LAV s and wild-type LSDV were developed. Upon validation, both assays were shown to have high sensitivity and specificity with a diagnostic performance comparable to ...

Characterisation of tetanus monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay.

could be a better choice and negate the need for an in vivo potency test. These immunochemical methods require at least one well characterised monoclonal antibody (mAb) that is specific for the target ...

HPV DNA genotyping, HPV E6*I mRNA detection, and p16INK4a/Ki-67 staining in Belgian head and neck cancer patient specimens, collected within the HPV-AHEAD study

DNA-negatives of the other HNC-sites were tested for the presence of type-specific HPV RNA and p16 over-expression. RESULTS: The highest HPV DNA prevalence was observed in OPC (36.4 %), and was significantly ...

Selection and use of reference panels: a case study highlighting current gaps in the materials available for foot and mouth disease.

comparative purposes and the calibration of test results across different laboratories. Using foot and mouth disease (FMD) as an example, this review highlights four specific areas where new reference reagents ...

Circulation of pertussis and poor protection against diphtheria among middle-aged adults in 18 European countries.

IgG- DTP specific antibodies. The proportion of sera with pertussis toxin antibody levels ≥100 IU /mL, indicative of recent exposure to pertussis was comparable for 13/18 countries, ranging between ...

Burden of disease methods: A guide to calculate COVID-19 Disability-Adjusted Life Years

date, published studies have only included one COVID-19 related health state, or disability weights were country-specific [7–9]. Health Topics:  Burden of disease COVID-19 Fardeau de la maladie Ziektelast ...

A molecular assay for rapidly distinguishing the AviPro SALMONELLA VAC T vaccine strain from wild-type field isolates

resistance testing, but this sometime leads to ambiguous results with major economic implications. In this study, we used whole-genome sequencing to identify conserved and specific mutations in resistance and virulence ...

Hoge Gezondheidsraad. Vegetarische voeding Brussel: HGR; 2021. Advies nr. 9445

infants, children, pregnant woman, nursing mothers and seniors with specific recommendations that allow them to avoid nutritional deficiencies or toxic risks related to their food choices. Versie gevalideerd ...

Belgian rare diseases plan in clinical pathology: identification of key biochemical diagnostic tests and establishment of reference laboratories and financing conditions.

Humans Laboratories Rare diseases Abstract: BACKGROUND: One objective of the Belgian Rare Diseases plan is to improve patients’ management using phenotypic tests and, more specifically, the access to those ...

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