Résultats de la recherche - 13 results
Speeding up drug susceptibility testing in Mycobacterium tuberculosis using RNA biomarkers
Tuberculosis; Antimicrobial resistance; Diagnosis; RNA Biomarkers Abstract: Background Efficient management of drug-resistant tuberculosis relies on fast diagnostics. To accelerate phenotypic drug susceptibility ...
The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.
Walker; CRyPTIC Consortium; Seq&Treat Consortium; Derrick W Crook; Nazir Ismail; Timothy C Rodwell; Vanessa Mathys Source: Lancet Microbe, Volume 3, Issue 4 (2022) Keywords: Drug Resistance mutations ...
Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.
Organization priority. We previously developed a software tool,, which provided offline species identification and drug resistance predictions for from whole genome sequencing (WGS) data. Performance was ...
RNA-based drug susceptibility testing of Mycobacterium tuberculosis
Pieter-Jan Ceyssens Source: 39th Annual Congress of the European Society of Mycobacteriology, Issue ESM, Dresden, Germany (2018) Keywords: drug susceptibility testing Mycobacterium tuberculosis Health Topics: ...
A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.
profiles; phenotypic resistance to isoniazid, rifampicin, ethambutol, pyrazinamide, and capreomycin; and corresponding drug resistance mutations. We whole-genome sequenced all Mycobacterium tuberculosis ...
Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.
Volume 22, Issue 1 (2018) Keywords: Carbapenems repurposed drugs XDR-TB Abstract: BACKGROUND: Extensively drug-resistant tuberculosis (XDR- TB), defined as TB caused by a Mycobacterium strain resistant to ...
Molecular epidemiology of Mycobacterium tuberculosis complex in Brussels, 2010-2013.
Maryse; Saegerman, Claude; Vanessa Mathys Source: PLoS One, Volume 12, Issue 2, p.e0172554 (2017) Keywords: ADOLESCENT Adult Bacterial Typing Techniques Belgium Child Cluster Analysis Contact Tracing Drug ...
MALDI-TOF for the identification of Mycobacteria and their drug resistance profiles
Mycobacteria. 34 clinical M. tuberculosis isolates were investigated for their resistance profile to four different drugs (rifampicin, isoniazid, ethambutol and linezolid), yielding a 100% concordance to the ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
recent report of the WHO ranks tuberculosis (TB) alongside HIV as a leading cause of death by infectious diseases. In combination, the spread of (multi-)drug resistant Mycobacterium tuberculosis is rising ...
Global transcriptional analyses of Mycobacterium tuberculosis using old and new drugs
(TB) alongside HIV as a leading cause of death by infectious diseases. In combination, the spread of (multi-)drug resistant Mycobacterium tuberculosis is rising (480 000 new cases), impeding the ...