Zoekresultaten - 117 results
Shotgun metagenomics as a ONE Health tool for better protecting human health
food-borne outbreak that occurred in Belgium in 2019. Discussion: By applying the shotgun metagenomics approach to specific case studies, we delivered proof-of-concepts and demonstrated its added value ...
OMCL testing and the API working group: Part of the solution?
presentation the new concept of the combined CAP / MSS / MSSFP studies is presented as well as a summary of the first MSSFP study of this kind on sildenafil citrate (MSSFP004) and this for both the set-up of the ...
Concept paper on the change in testing strategy for purity test on monovalent bulk of recombinant protein vaccine
Publication Type: Sci. report, recommendat°, guidance doc., directive, monograph Authors: L. Tesolin; M. Bruysters Source: EDQM, Strasbourg, France, p.5 (2022) Accession Number: PA/PH/OMCL (22) 52 DEF Keywords: control strategy OMCL recombinant protein va ...
Development and validation of a microfluidic multiplex immunoassay for the determination of levels and avidity of serum antibodies to tetanus, diphtheria and pertussis antigens.
correlation coefficients between 0.936 for PT and 0.982 for DT xd (p < 0.0001 for all). Finally, we showed in a proof-of-concept experiment the potential of the Evalution® platform to simultaneously measure ...
Estimating risk factor attributable burden – challenges and potential solutions when using the comparative risk assessment methodology
as these concepts are sometimes referred to synonymously but have distinctly different applications. Results. CRA s are very data demanding. One key element is the exposure-response relationship ...
Citizens’ perception of and engagement with health data secondary use and sharing in Europe – a literature review
concept of data ownership. Some authors do contest its applicability in the context on health data, and the myth that it provides absolute control to the owner. Several authors defend other approaches, such ...
Health expectancies in the European Union: same concept, different methods, different results
Publication Type: Peer reviewed scientific article Authors: João Vasco Santos; João Viana; Brecht Devleesschauwer; Juanita A Haagsma; Cristina Costa Santos; Walter Ricciardi; Alberto Freitas Source: Journal of Epidemiology and Community Health, Volume 75, ...
Application of a strain-level shotgun metagenomics approach on food samples: resolution of the source of a Salmonella food-borne outbreak
2 weeks after receipt of the sample, which was freshly prepared tartar sauce in a meal cooked at the school. Our team used this outbreak as a case study to deliver a proof of concept for a short-read ...
Development of a multiplex immunoassay for simultaneous detection of antigens in DTaP vaccines
antibody of the sandwich assay to determine the most favorable combination to use in the multiplex assay (better signal-to-noise ratio). As a proof of concept, the potency of 18 batches from HuB was compared ...
Targeted LC-MS/MS combined with multilocus DNA metabarcoding as a combinatory approach to determine the amount and the source of pyrrolizidine alkaloids contamination in popular cooking herbs, seeds, spices and leafy vegetables.
levels. As a proof of concept, multilocus DNA metabarcoding was performed on six highly contaminated samples, belonging to each subtype matrix, containing high levels of heliotrine type of PA / PANO s. Each ...