Zoekresultaten - 24 results

Speeding up drug susceptibility testing in Mycobacterium tuberculosis using RNA biomarkers

and contribute to drug discovery and development. Health Topics:  Tuberculosis Tuberculose Tuberculose Manuscript versions:  DOI:  https://doi.org/10.1016/j.ebiom.2025.105611 File:  Version:  Published ...

The 2021 WHO catalogue of complex mutations associated with drug resistance: A genotypic analysis.

interpretation. Its existence should encourage the implementation of molecular diagnostics by National Tuberculosis Programmes. Funding: UNITAID, Wellcome, MRC, BMGF. Health Topics:  Tuberculosis Tuberculose ...

Multicentre study on the reproducibility of MALDI-TOF MS for nontuberculous mycobacteria identification.

procedure or to MALDI- TOF system status in each centre. In conclusion, MALDI- TOF showed to be a highly reproducible method and suitable for its implementation for NTM  identification. Health Topics:  ...

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe.

billion people are infected with, leading to 10 million new cases of active tuberculosis and 1.5 million deaths annually. Universal access to drug susceptibility testing (DST) has become a World Health ...

Strong increase of true and false positive mycobacterial cultures sent to the National Reference Centre in Belgium, 2007 to 2016.

at the NRC, highlighting the importance of sample decontamination/transport and equipment calibration in peripheral laboratories. Health Topics:  Tuberculosis Tuberculose Tuberculose Manuscript ...

RNA-based drug susceptibility testing of Mycobacterium tuberculosis

Pieter-Jan Ceyssens Source: 39th Annual Congress of the European Society of Mycobacteriology, Issue ESM, Dresden, Germany (2018) Keywords: drug susceptibility testing Mycobacterium tuberculosis Health Topics:  ...

Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study.

justify their resource and personnel needs for the implementation of novel, time-saving, cost-effective technologies, as well as identify areas for improvement. Health Topics:  Tuberculosis Tuberculose ...

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study.

shared mutation of tlyA is a drug resistance mutation and phylogenetic marker, the first of its kind in M tuberculosis sensu stricto. FUNDING: The Swiss Federal Office of Public Health, the University of ...

Meropenem-clavulanate for drug-resistant tuberculosis: a follow-up of relapse-free cases.

at least rifampicin, isoniazid, any fluoroquinolone and one of the injectable anti-tuberculosis drugs, remains a worldwide public health threat. Among repurposed drugs empirically used for XDR- TB ...

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